4,5-二甲基苯-1,2-二甲醇合成路线 （共 7 条）
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=-78 - 20°C; Reflux; 2: With phosphorus tribromide
参考文献
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Patent: US2012/4476 A1, 2012 ;
Location in patent: Page/Page column 9 ;
反应条件
methanol; sodium tetrahydroborate in tetrahydrofuran 18 h; Reflux;
参考文献
Jagtap, Subodh P.; Mukhopadhyay, Sukrit; Coropceanu, Veaceslav; Brizius, Glen L.; Bredas, Jean-Luc; Collard, David M.
Journal of the American Chemical Society, 2012 , vol. 134, # 16 p. 7176 - 7185
反应条件
1: concentrated aqueous HCl / 60 - 70 °C / Einleiten von HCl 2: glacial acetic acid / Behandeln des oeligen Reaktionsprodukts mit Alkalilauge View Scheme
参考文献
Chemische Berichte, , vol. 67, p. 1094,1096
反应条件
acetic acid Behandeln des oeligen Reaktionsprodukts mit Alkalilauge;
参考文献
Chemische Berichte, , vol. 67, p. 1094,1096
反应条件
1: With oxalyl dichloride; dimethyl sulfoxide in dichloromethane T=-78°C; Swern oxidation; 0.5 h; Inert atmosphere; 2: With triethylamine in dichloromethane T=-78 - 20°C; Swern oxidation; Inert atmosphere;
参考文献
Montavon, Timothy J.; Tuerkmen, Yunus E.; Shamsi, Noumaan A.; Miller, Christopher; Sumaria, Chintan S.; Rawal, Viresh H.; Kozmin, Sergey A.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 51 p. 13576 - 13579
Angew. Chem., 2013 , vol. 125, # 51 p. 13821 - 13824,4
反应条件
1: PBr3 / diethyl ether; benzene
2: Na, tetraphenyl-ethene / tetrahydrofuran / -80 °C
View Scheme
参考文献
Brickwood,D.J. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1978 , p. 1398 - 1414
反应条件
Oxonereg;; 2-iodo-3,4,5,6-tetramethylbenzoic acid in water; acetonitrile
T=30°C; 15 h; Green chemistry;
参考文献
Jhulki, Samik; Seth, Saona; Mondal, Manas; Moorthy, Jarugu Narasimha
Tetrahedron, 2014 , vol. 70, # 13 p. 2286 - 2293
