(2-溴-5-甲氧基苯基)(苯基)甲酮合成路线 （共 9 条）
反应条件
silica gel; pyridinium chlorochromate in dichloromethane
T=20°C; 2 h; Inert atmosphere;
参考文献
Mahendar, Lodi; Satyanarayana, Gedu
Journal of Organic Chemistry, 2014 , vol. 79, # 5 p. 2059 - 2074
反应条件
1: 2-bromo-5-methoxy benzoic acid With thionyl chloride
T=80°C; 2 h; Inert atmosphere;
2: benzene With AlCl3, aluminium chloride
T=80°C; Friedel-Crafts Acylation; 1 h; Inert atmosphere;
参考文献
Nagahora, Noriyoshi; Wasano, Tatsuya; Nozaki, Kazuhiro; Ogawa, Tamaki; Nishijima, Shuhei; Motomatsu, Daiki; Shioji, Kosei; Okuma, Kentaro
European Journal of Organic Chemistry, 2014 , vol. 2014, # 7 p. 1423 - 1430
反应条件
1: thionyl chloride / CHCl3 / 3 h / Heating
2: 2.3 g / aluminum chloride / 6 h / Heating
View Scheme
参考文献
Inamoto, Kiyofumi; Katsuno, Mika; Yoshino, Takashi; Arai, Yukari; Hiroya, Kou; Sakamoto, Takao
Tetrahedron, 2007 , vol. 63, # 12 p. 2695 - 2711
反应条件
1: PhMgCl / tetrahydrofuran / 1 h / -5 °C
2: 37.4 g / tetrahydrofuran / 5 h / -10 - 25 °C
View Scheme
参考文献
Reynolds, Dominic J; Hermitage, Stephen A
Tetrahedron, 2001 , vol. 57, # 36 p. 7765 - 7770
反应条件
in tetrahydrofuran
T=-10 - 25°C; 5 h;
参考文献
Reynolds, Dominic J; Hermitage, Stephen A
Tetrahedron, 2001 , vol. 57, # 36 p. 7765 - 7770
反应条件
1: tetrahydrofuran / 3 h / 0 - 20 °C / |Inert atmosphere
2: pyridinium chlorochromate; silica gel / dichloromethane / 2 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
Mahendar, Lodi; Satyanarayana, Gedu
Journal of Organic Chemistry, 2014 , vol. 79, # 5 p. 2059 - 2074
反应条件
1: tetrahydrofuran / 3 h / 0 - 20 °C / |Inert atmosphere
2: pyridinium chlorochromate; silica gel / dichloromethane / 2 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
Mahendar, Lodi; Satyanarayana, Gedu
Journal of Organic Chemistry, 2014 , vol. 79, # 5 p. 2059 - 2074
反应条件
AlCl3, aluminium chloride
1 h; Reflux;
参考文献
Tian, Yulin; Qi, Jianguo; Sun, Chenbin; Yin, Dali; Wang, Xiaojian; Xiao, Qiong
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 42 p. 7262 - 7266
反应条件
aluminium trichloride
6 h; Heating;
参考文献
Inamoto, Kiyofumi; Katsuno, Mika; Yoshino, Takashi; Arai, Yukari; Hiroya, Kou; Sakamoto, Takao
Tetrahedron, 2007 , vol. 63, # 12 p. 2695 - 2711
