1-(2-甲基-1H-吡咯-3-基)-乙酮合成路线 （共 16 条）
反应条件
trifluoroacetic acid in dichloromethane
T=0 - 20°C;
参考文献
Bellur, Esen; Langer, Peter
Tetrahedron Letters, 2006 , vol. 47, # 13 p. 2151 - 2154
反应条件
diisobutylaluminium hydride in tetrahydrofuran
T=-50°C; 5 h;
参考文献
Alberola, Angel; Ortega, Alfonso Gonzalez; Sadaba, M. Luisa; Sanudo, Carmen
Tetrahedron, 1999 , vol. 55, # 21 p. 6555 - 6566
反应条件
trifluoroacetic acid in dichloromethane
T=0 - 20°C; 12 h; Inert atmosphere;
参考文献
Bellur, Esen; Yawer, Mirza A.; Hussain, Ibrar; Riahi, Abdolmajid; Fatunsin, Olumide; Fischer, Christine; Langer, Peter
Synthesis, 2009 , # 2 p. 227 - 242
反应条件
Keggin-type heteropolyacid
T=20°C; 6 h; Neat (no solvent);
参考文献
Hekmatshoar, Rahim; Sadjadi, Sodeh; Sadjadi, Samaheh; Heravi, Majid M.; Beheshtiha, Yahya S.; Bamoharram, Fatemeh F.
Synthetic Communications, 2010 , vol. 40, # 11 p. 1708 - 1716
反应条件
1: 91 percent / hydrogen, triethylamine / 10percent Pd/C / tetrahydrofuran / 3 h
2: 61 percent / trifluoroacetic acid / 1 h / Heating
View Scheme
参考文献
Clezy, Peter S.; Salek, Abdoreza
Australian Journal of Chemistry, 1996 , vol. 49, # 3 p. 265 - 272
反应条件
in dimethyl sulfoxide
T=150°C; 24 h; Inert atmosphere;
参考文献
Bellur, Esen; Yawer, Mirza A.; Hussain, Ibrar; Riahi, Abdolmajid; Fatunsin, Olumide; Fischer, Christine; Langer, Peter
Synthesis, 2009 , # 2 p. 227 - 242
反应条件
ammonium hydroxide
T=74°C; 1 h;
参考文献
Baggs, Marion E. M.; Gregory, Brian
Canadian Journal of Chemistry, 1980 , vol. 58, p. 794 - 802
反应条件
in trifluoroacetic acid
1 h; Heating;
参考文献
Clezy, Peter S.; Salek, Abdoreza
Australian Journal of Chemistry, 1996 , vol. 49, # 3 p. 265 - 272
反应条件
in dimethyl sulfoxide
T=150°C; 24 h;
参考文献
Bellur, Esen; Langer, Peter
Tetrahedron Letters, 2006 , vol. 47, # 13 p. 2151 - 2154
反应条件
1: 81 percent / methanol / 10 h / 35 °C
2: 62 percent / DIBAL-H / tetrahydrofuran / 5 h / -50 °C
View Scheme
参考文献
Alberola, Angel; Ortega, Alfonso Gonzalez; Sadaba, M. Luisa; Sanudo, Carmen
Tetrahedron, 1999 , vol. 55, # 21 p. 6555 - 6566
