四(2-氯乙基)磷酰氯二胺合成路线 （共 4 条）
反应条件
triethylamine; trichlorophosphate in toluene
参考文献
TELIK, INC.
Patent: EP1278759 B1, 2005 ;
反应条件
triethylamine; trichlorophosphate in toluene
T=20°C; 26 h; Heating / reflux;
参考文献
Allen, David R.; Ma, Wenli; Peterson, Brian T.; Robinson, Louise; Schow, Steven R.; Shi, Songyuan; Simon, Reyna J.; Weber, Kevin T.; Wick, Michael M.
Patent: US2005/267075 A1, 2005 ;
Location in patent: Page/Page column 41 ;
反应条件
triethylamine in toluene
16 h; Heating;
参考文献
Borch, Richard F.; Valente, Ronald R.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 10 p. 3052 - 3058
反应条件
triethylamine in toluene
20 h; RefluxLarge scale;
参考文献
Herr, R. Jason; Zhichkin, Paul; Hernandez-Abad, Pedro E.; Meckler, Harold; Schow, Steven R.
Organic Process Research and Development, 2001 , vol. 5, # 4 p. 442 - 444
