S-2-硝基苯基-L-半胱氨酸合成路线 (共 7 条)
反应条件
sulfuric acid in water
0.5 h; Heating;
参考文献
Slade; Stanton; Ben-David; Mazzenga
Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1517 - 1521
反应条件
triethylamine in N,N-dimethyl-formamide
3 h; Ambient temperature;
参考文献
Dua; Taylor; Phillips
Journal of the American Chemical Society, 1993 , vol. 115, # 4 p. 1264 - 1270
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=80°C; 4 h;
参考文献
Xue; Voss; Nelson; Duan; Cherney; Jacobson; He; Roderick; Chen; Corbett; Wang; Meyer; Kennedy; Degrado; Hardman; Teleha; Jaffee; Liu; Copeland; Covington; Christ; Trzaskos; Newton; Magolda; Wexler; Decicco
Journal of Medicinal Chemistry, 2001 , vol. 44, # 16 p. 2636 - 2660
反应条件
sodium nitrite
Ambient temperature;
参考文献
Itoh; Kori; Inada; Nishikawa; Kawamatsu; Sugihara
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 3 p. 1128 - 1147
反应条件
ammonium hydroxide in ethanol
参考文献
Tamaki, Hisanori; Kumagai, Hidehiko; Shimada, Yoshimi; Kashima, Takanori; Obata, Hiroshi; et al
Agricultural and Biological Chemistry, 1991 , vol. 55, # 4 p. 951 - 956
参考文献
Shchukina,L.A. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1970 , vol. 40, # 7 p. 1667,1657
反应条件
(i) Zn, aq. H2SO4, (ii) /BRN= 4776722/, Cu2O; Multistep reaction;
参考文献
Boyland,E. et al.
Journal of the Chemical Society, 1962 , p. 606 - 611