2,6-二氟-3-硝基吡啶-4-胺合成路线 （共 6 条）
反应条件
sulfuric acid
T=20°C;
参考文献
Liu; Luo; Mozdziesz; Lin; Dutschman; Gullen; Cheng; Sartorelli
Nucleosides, Nucleotides and Nucleic Acids, 2001 , vol. 20, # 12 p. 1975 - 2000
反应条件
1: 33 percent / Et3N; H2 / 10 percent Pd/C / ethanol / 18 h / 2585.74 Torr
2: 76 percent / conc. H2SO4; KNO3 / 0 - 20 °C
3: 89 percent / conc. H2SO4 / 20 °C
View Scheme
参考文献
Liu; Luo; Mozdziesz; Lin; Dutschman; Gullen; Cheng; Sartorelli
Nucleosides, Nucleotides and Nucleic Acids, 2001 , vol. 20, # 12 p. 1975 - 2000
反应条件
1: 98 percent / aq. NH4OH / 20 °C
2: 33 percent / Et3N; H2 / 10 percent Pd/C / ethanol / 18 h / 2585.74 Torr
3: 76 percent / conc. H2SO4; KNO3 / 0 - 20 °C
4: 89 percent / conc. H2SO4 / 20 °C
View Scheme
参考文献
Liu; Luo; Mozdziesz; Lin; Dutschman; Gullen; Cheng; Sartorelli
Nucleosides, Nucleotides and Nucleic Acids, 2001 , vol. 20, # 12 p. 1975 - 2000
反应条件
1: 76 percent / conc. H2SO4; KNO3 / 0 - 20 °C
2: 89 percent / conc. H2SO4 / 20 °C
View Scheme
参考文献
Liu; Luo; Mozdziesz; Lin; Dutschman; Gullen; Cheng; Sartorelli
Nucleosides, Nucleotides and Nucleic Acids, 2001 , vol. 20, # 12 p. 1975 - 2000
反应条件
hydrogen; nickel in ethanol
参考文献
Liu; Luo; Mozdziesz; Lin; Dutschman; Gullen; Cheng; Sartorelli
Nucleosides, Nucleotides and Nucleic Acids, 2001 , vol. 20, # 12 p. 1975 - 2000
反应条件
1: 92 percent / H2 / Raney Ni / ethanol
View Scheme
参考文献
Liu; Luo; Mozdziesz; Lin; Dutschman; Gullen; Cheng; Sartorelli
Nucleosides, Nucleotides and Nucleic Acids, 2001 , vol. 20, # 12 p. 1975 - 2000
