N-(1H-吲哚-5-基)苯甲酰胺合成路线 （共 6 条）
反应条件
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in N,N-dimethyl-formamide
T=20°C;
参考文献
ASTEX TECHNOLOGY LIMITED
Patent: WO2003/87087 A2, 2003 ;
Location in patent: Page/Page column 39 ;
WO 03/087087 A2
反应条件
triethylamine in tetrahydrofuran
参考文献
Macor; Blank; Fox; Lebel; Newman; Post; Ryan; Schmidt; Schulz; Koe
Journal of Medicinal Chemistry, 1994 , vol. 37, # 16 p. 2509 - 2512
反应条件
1: acetic acid anhydride; nitric acid / 10 °C / Erhitzen des Reaktionsprodukts mit konz. wss. Salzsaeure
2: tetrachloro-<1,4>benzoquinone; xylene
3: N2H4+H2O; Raney nickel; ethanol
4: aqueous alkali; benzene
View Scheme
参考文献
Terent'ew et al.
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 2541,2550; engl. Ausg. S. 2504, 2511
反应条件
1: tetrachloro-<1,4>benzoquinone; xylene
2: N2H4+H2O; Raney nickel; ethanol
3: aqueous alkali; benzene
View Scheme
参考文献
Terent'ew et al.
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 2541,2550; engl. Ausg. S. 2504, 2511
反应条件
1: aq.-ethanolic hydrochloric acid
2: tetrachloro-<1,4>benzoquinone; xylene
3: N2H4+H2O; Raney nickel; ethanol
4: aqueous alkali; benzene
View Scheme
参考文献
Terent'ew et al.
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 2541,2550; engl. Ausg. S. 2504, 2511
反应条件
1: N2H4+H2O; Raney nickel; ethanol
2: aqueous alkali; benzene
View Scheme
参考文献
Terent'ew et al.
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 2541,2550; engl. Ausg. S. 2504, 2511
