1,1'-联-2-萘酚合成路线 （共 233 条）
反应条件
1: 91 percent / Nafion-NR50 ion-exchange resin / o-xylene / 16 h / Heating 2: 68 percent / glac. HOAc / 0.17 h / Heating View Scheme
参考文献
Uozumi, Yasuhiro; Tanahashi, Asako; Lee, Sang-Yong; Hayashi, Tamio
Journal of Organic Chemistry, 1993 , vol. 58, # 7 p. 1945 - 1948
反应条件
1: 100 percent / pyridine / CH2Cl2 / 6 h / 0 °C 2: 95 percent / diisopropylethylamine / palladium diacetate, 1,4-bis(diphenylphosphino)butane / dimethylsulfoxide / 12 h / 100 °C 3: 99 percent / 3N aq. NaOH / methanol; dioxane / 12 h / Ambient temperature 4: 92 percent / K2CO3 / acetone / Heating 5: 84 percent / NEt3, Cl3SiH / xylene / 120 °C View Scheme
参考文献
Uozumi, Yasuhiro; Tanahashi, Asako; Lee, Sang-Yong; Hayashi, Tamio
Journal of Organic Chemistry, 1993 , vol. 58, # 7 p. 1945 - 1948
反应条件
1.1: 95 percent / pyridine / toluene / 3.5 h / 0 - 25 °C 2.1: Mg / tetrahydrofuran / Heating 2.2: 80 percent / NiCl2(dppp) / tetrahydrofuran / 0.5 h / Heating View Scheme
参考文献
Ooi, Takashi; Kameda, Minoru; Maruoka, Keiji
Journal of the American Chemical Society, 1999 , vol. 121, # 27 p. 6519 - 6520
反应条件
1.1: NaH / dimethylformamide / 5 h / 0 °C 2.1: TMEDA; BuLi / tetrahydrofuran; hexane / 0.5 h / 0 °C 2.2: 76 percent / tetrahydrofuran; hexane / 1.17 h / -78 - 0 °C 3.1: NaBH4 / tetrahydrofuran / 0.25 h / 0 °C 4.1: Et3N / toluene / 1.5 h / 0 °C 5.1: LiBr / dimethylformamide / 0.17 h / 20 °C 6.1: NaH / tetrahydrofuran; dimethylformamide / 1 h / 0 °C 6.2: 82 percent / tetrahydrofuran; dimethylformamide / 64 h / 20 °C 7.1: 85 percent / TsOH*H2O / CH2Cl2; methanol / 36 h / 40 °C View Scheme
参考文献
Matsunaga; Das; Roels; Vogl; Yamamoto; Iida; Yamaguchi; Shibasaki
Journal of the American Chemical Society, 2000 , vol. 122, # 10 p. 2252 - 2260
反应条件
sodium hydrogencarbonate; potassium carbonate T=10°C; Williamson synthesis; 5 h;
参考文献
Massah, Ahmad R.; Mosharafian, Masumeh; Momeni, Ahamad R.; Aliyan, Hamid; Naghash, H. Javaherian; Adibnejad, Mohamad
Synthetic Communications, 2007 , vol. 37, # 11 p. 1807 - 1815
参考文献
Yang, Hua; Petersen, Jeffrey L.; Wang, Kung K.
Tetrahedron, 2006 , vol. 62, # 34 p. 8133 - 8141
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran; toluene 24 h; Ambient temperature;
参考文献
Takahashi, Michiyasu; Ogasawara, Kunio
Tetrahedron Asymmetry, 1997 , vol. 8, # 18 p. 3125 - 3130
反应条件
potassium carbonate in acetone
参考文献
Yashima, Eiji; Yamamoto, Chiyo; Okamoto, Yoshio
Journal of the American Chemical Society, 1996 , vol. 118, # 17 p. 4036 - 4048
参考文献
Salvadori, Piero; Rosini, Carlo; Pini, Dario; Bertucci, Carlo; Altemura, Paolo; et. al
Tetrahedron, 1987 , vol. 43, # 21 p. 4969 - 4978
反应条件
pyridine in dichloromethane T=0°C; 6 h;
参考文献
Uozumi, Yasuhiro; Tanahashi, Asako; Lee, Sang-Yong; Hayashi, Tamio
Journal of Organic Chemistry, 1993 , vol. 58, # 7 p. 1945 - 1948
