2,3,4,5,6-五氟苯甲酸合成路线 （共 133 条）
反应条件
1: 96 percent / conc. H2SO4 / CCl4 / Heating 2: 87 percent / NaN3 / acetone; H2O / 8 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 55, # 11 p. 3640 - 3647
反应条件
1: aq. NaOH, NaHS / 2 h / 70 °C 2: 978 mg / 30percent H2O2, AcOH / 2 h / 70 °C 3: SOCl2, DMF / 6 h / Heating View Scheme
参考文献
Fielding, H. C.; Shirley, I. M.
Journal of Fluorine Chemistry, 1992 , vol. 59, # 1 p. 15 - 31
反应条件
4-(N,N-dimethlyamino)pyridine; C21H27AuN2 in dichloromethane T=40°C; 12 h; Inert atmosphere;
参考文献
Lv, Hongbin; Zhan, Jin-Hui; Cai, Yuan-Bo; Yu, Yi; Wang, Bingwu; Zhang, Jun-Long
Journal of the American Chemical Society, 2012 , vol. 134, # 39 p. 16216 - 16227,12
反应条件
sodium methylate in methanol; ethyl acetate
参考文献
IMPERIAL CHEMICAL INDUSTRIES PLC
Patent: EP266947 B1, 1991 ;
反应条件
dicyclohexyl-carbodiimide in toluene Ambient temperature;
参考文献
Weintraub, Susan T.; Satsangi, Rajiv K.; Simmons, Anne Marie; Williams, Robert F.; Neal Pinckard
Analytical Chemistry, 1993 , vol. 65, # 17 p. 2400 - 2402
反应条件
1: BBr3 / benzene / Ambient temperature 2: 40 - 100 °C / 0.02 Torr View Scheme
参考文献
Sartori,P.; Weidenbruch,M.
Chemische Berichte, 1967 , vol. 100, p. 3016 - 3023
反应条件
t-Bu-XantPhos; tBuXantphosAu(AuCl2); (Ph)2SiH2; acetic acid in 1,2-dichloro-ethane T=80°C; 24 h; Inert atmosphere;
参考文献
Advanced Synthesis and Catalysis, , vol. 354, # 8 p. 1529 - 1541
反应条件
1,10-phenanthroline; nickel dichloride; zinc in water; N,N-dimethyl-formamide T=50°C; Hydrodefluorination; 6 h; Product distribution; Further Variations:ReagentsTemperaturesreaction time;
参考文献
Journal of Fluorine Chemistry, , vol. 101, # 1 p. 65 - 67
反应条件
1: 96 percent / conc. H2SO4 / CCl4 / Heating 2: 87 percent / NaN3 / acetone; H2O / 8 h / Heating 3: 98 percent / 20percent aq. NaOH / methanol; H2O / 25 °C 4: 99 percent / dicyclohexylcarbodiimide / CH2Cl2 / 25 °C View Scheme
参考文献
Keana, John F. W.; Cai, Sui Xiong
Journal of Organic Chemistry, 1990 , vol. 55, # 11 p. 3640 - 3647
反应条件
monohydrazine sulfate T=150 - 200°C; 4 h; Inert atmosphere;
参考文献
Zhao, Zhenhua; Ma, Xiaohua; Zhang, Aixin; Song, Naiheng
Journal of Polymer Science, Part A: Polymer Chemistry, 2011 , vol. 49, # 11 p. 2423 - 2433
