2,3,4,5,6-五氟苯甲酸合成路线 （共 133 条）
反应条件
hydrogenchloride; sodium hydroxide; NaSH; dihydrogen peroxide in water; acetic acid
参考文献
Imperial Chemical Industries PLC
Patent: US5169983 A1, 1992 ;
反应条件
1: aq. NaOH, NaHS / 2 h / 70 °C 2: 978 mg / 30percent H2O2, AcOH / 2 h / 70 °C View Scheme
参考文献
Fielding, H. C.; Shirley, I. M.
Journal of Fluorine Chemistry, 1992 , vol. 59, # 1 p. 15 - 31
反应条件
NiCl2*3Bpy; [N-butylthiazolium][Br]; zinc in water T=70°C; 7 h;
参考文献
Prikhod'ko, Sergey A.; Adonin, Nicolay Yu.; Parmon, Valentin N.
Tetrahedron Letters, 2010 , vol. 51, # 17 p. 2265 - 2268
反应条件
[Fe(II)(TPA)(CH3CN)2](OTf)2; water; dihydrogen peroxide in acetonitrile T=20°C;
参考文献
Das, Parthapratim; Que Jr., Lawrence
Inorganic Chemistry, 2010 , vol. 49, # 20 p. 9479 - 9485
反应条件
triphenylphosphine; silver carbonate; palladium dichloride in dimethyl sulfoxide T=130°C; 6 h; Inert atmosphere;
参考文献
European Journal of Organic Chemistry, , # 29 p. 5787 - 5790
反应条件
triphenylphosphine; silver carbonate; palladium dichloride in dimethyl sulfoxide T=130°C; 6 h; Inert atmosphere;
参考文献
Xie, Kai; Wang, Sizhuo; Yang, Zhiyong; Liu, Jidan; Wang, Anwei; Li, Xiujian; Tan, Ze; Guo, Can-Cheng; Deng, Wei
European Journal of Organic Chemistry, 2011 , # 29 p. 5787 - 5790
反应条件
1: 96 percent / conc. H2SO4 / CCl4 / Heating 2: 87 percent / NaN3 / acetone; H2O / 8 h / Heating 3: 98 percent / 20percent aq. NaOH / methanol; H2O / 25 °C 4: 70 percent / SOCl2 / CH2Cl2 / 36 h / Heating View Scheme
参考文献
Keana, John F. W.; Cai, Sui Xiong
Journal of Organic Chemistry, 1990 , vol. 55, # 11 p. 3640 - 3647
反应条件
Ag2CO3; oxygen; palladium diacetate in dimethyl sulfoxide T=130°C; 12 h; Sealed tube; Reagent/catalystSolventTemperatureTime;
参考文献
Tetrahedron Letters, , vol. 54, # 22 p. 2833 - 2836
反应条件
1,4-diaza-bicyclo[2.2.2]octane; tert.-butylhydroperoxide; copper dichloride in water; 1,2-dichloro-ethane
T=80°C; Schlenk techniqueInert atmosphere;
参考文献
Xie, Ye-Xiang; Song, Ren-Jie; Yang, Xu-Heng; Xiang, Jian-Nan; Li, Jin-Heng
European Journal of Organic Chemistry, 2013 , # 25 p. 5737 - 5742
反应条件
Ag2CO3; oxygen; palladium diacetate in dimethyl sulfoxide
T=130°C; Sealed tube; Overall yield = 70 percent;
参考文献
Luo, Hai-Qing; Dong, Wen; Loh, Teck-Peng
Tetrahedron Letters, 2013 , vol. 54, # 22 p. 2833 - 2836
