potassium tert-butylate in dimethyl sulfoxide T=20°C; 1 h;

potassium tert-butylate in tetrahydrofuran

1.1: acetonitrile / 0.5 h / 0 °C 1.2: 51 percent / NaI / acetonitrile / 2 h / 50 °C 2.1: diisopropylamine; n-BuLi / tetrahydrofuran; hexane / 1 h / -78 °C 2.2: 65 percent / tetrahydrofuran; hexane / -78 °C 3.1: 68 percent / tert-BuOK / tetrahydrofuran View Scheme

1.1: diisopropylamine; n-BuLi / tetrahydrofuran; hexane / 1 h / -78 °C 1.2: 65 percent / tetrahydrofuran; hexane / -78 °C 2.1: 68 percent / tert-BuOK / tetrahydrofuran View Scheme

hydrogenchloride; sodium nitrite anschl. mit Hypophosphorigsaeure, wss. Salzsaeure und Kupfer(II)-sulfat;

1: H2S; ethanol; aqueous NH3 2: aqueous hydrochloric acid; sodium nitrite / anschl. mit Hypophosphorigsaeure, wss. Salzsaeure und Kupfer(II)-sulfat View Scheme