2-甲基-3-羟基苯甲酸合成路线 （共 39 条）
反应条件
1: With sulfuric acid; sodium nitrite in water T=7°C; 0.5 h; 2: With sulfuric acid; water; urea in water T=90°C;
参考文献
Syntex (U.S.A.) LLC
Patent: US6335/459 B1, 2002 ;
Location in patent: Page column 29 ;
Title/Abstract Full Text Show Details
Syntex (U.S.A.) LLC
Patent: US6335459 B1, 2002 ;
Location in patent: Page column 29 ;
US 6335459 B1
反应条件
potassium tert-butylate in toluene; tert-butyl alcohol
参考文献
Rohm and Haas Company
Patent: US6288260 B1, 2001 ;
反应条件
sodium nitrite in water; acetic acid
参考文献
Warner-Lambert Company
Patent: US6133303 A1, 2000 ;
US 6133303 A
反应条件
hydrogenchloride; sulfuric acid; urea; sodium nitrite in methanol; (2S)-N-methyl-1-phenylpropan-2-amine hydrate; water
参考文献
G. D. Searle and Co.
Patent: US6143747 A1, 2000 ;
US 6143747 A
反应条件
sodium hydroxide; nitrogen in water; dimethyl sulfoxide; ethyl acetate
反应条件
sodium hydroxide; nitrogen in water; dimethyl sulfoxide; ethyl acetate
反应条件
sodium hydroxide T=250°C;
参考文献
DE91201 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 4, p. 148
反应条件
1.1: 98 percent / H2 / Pd/C / ethanol / 20 °C 2.1: NaNO2; H2SO4 / H2O / 0 °C 2.2: 99 percent / aq. H2SO4 / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 11 p. 1741 - 1745
反应条件
sodium hydroxide T=250°C;
参考文献
DE91201 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 4, p. 148
