6-溴-2-甲基-4-硝基吡啶-n-氧化物合成路线 （共 3 条）
反应条件
iron; acetic acid T=20°C; 1 h;
参考文献
SIRTRIS PHARMACEUTICALS, INC.; CASAUBON, Rebecca, L.; NARAYAN, Radha; OALMANN, Christopher; VU, Chi, B.
Patent: WO2013/59587 A1, 2013 ;
Location in patent: Page/Page column 166 ;
反应条件
sulfuric acid; nitric acid
T=0 - 90°C; 1.5 h;
参考文献
SIRTRIS PHARMACEUTICALS, INC.; CASAUBON, Rebecca, L.; NARAYAN, Radha; OALMANN, Christopher; VU, Chi, B.
Patent: WO2013/59587 A1, 2013 ;
Location in patent: Page/Page column 165; 166 ;
反应条件
1: 3-chloro-benzenecarboperoxoic acid / chloroform / 18 h / 65 °C / |Inert atmosphere
2: nitric acid; sulfuric acid / 16 h / 0 - 100 °C
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参考文献
Walton, James W.; Bourdolle, Adrien; Butler, Stephen J.; Soulie, Marine; Delbianco, Martina; McMahon, Brian K.; Pal, Robert; Puschmann, Horst; Zwier, Jurriaan M.; Lamarque, Laurent; Maury, Olivier; Andraud, Chantal; Parker, David
Chemical Communications, 2013 , vol. 49, # 16 p. 1600 - 1602
