3-(4-溴苯基)-3-(3-吡啶基)烯丙胺合成路线 （共 16 条）
反应条件
1: PBr3 / CH2Cl2 / Heating
2: H2O / 4 h / Ambient temperature
3: 70 percent / ClCOOCH2CCl3 / benzene / 2 h / Heating
4: 41 percent / dimethylformamide / 3 h / 80 °C
5: 1.25 g / H2NNH2*H2O / methanol / 5 h / 60 °C
View Scheme
参考文献
Carnmalm; De Paulis; Hogberg; et al.
1982 , vol. 36, # 2 B p. 91 - 99
反应条件
1: 63 percent / NaBH4, BF3*Et2O / tetrahydrofuran / 48 h / Ambient temperature
2: aq. H2SO4 / 0.5 h / 80 °C
View Scheme
参考文献
Carnmalm; De Paulis; Hogberg; et al.
1982 , vol. 36, # 2 B p. 91 - 99
反应条件
1: NaBH4, BF3*Et2O / tetrahydrofuran / 1.) 0 deg C, 7 h, 2.) room temperature, 50 h
2: aq. H2SO4 / 0.42 h
3: formic acid, water / 3 h / Heating
4: 70 percent / ClCOOCH2CCl3 / benzene / 2 h / Heating
5: 41 percent / dimethylformamide / 3 h / 80 °C
6: 1.25 g / H2NNH2*H2O / methanol / 5 h / 60 °C
View Scheme
参考文献
Carnmalm; De Paulis; Hogberg; et al.
1982 , vol. 36, # 2 B p. 91 - 99
反应条件
1: LiAlH4 / tetrahydrofuran / 1.) 0 deg C, 2 h, 2.) 15 deg C, 2 h
2: aq. H2SO4 / 0.5 h / 80 °C
View Scheme
参考文献
Carnmalm; De Paulis; Hogberg; et al.
1982 , vol. 36, # 2 B p. 91 - 99
反应条件
1: aq. H2SO4 / 0.42 h
2: formic acid, water / 3 h / Heating
3: 70 percent / ClCOOCH2CCl3 / benzene / 2 h / Heating
4: 41 percent / dimethylformamide / 3 h / 80 °C
5: 1.25 g / H2NNH2*H2O / methanol / 5 h / 60 °C
View Scheme
参考文献
Carnmalm; De Paulis; Hogberg; et al.
1982 , vol. 36, # 2 B p. 91 - 99
反应条件
sulfuric acid
T=80°C; 0.5 h;
参考文献
Carnmalm; De Paulis; Hogberg; et al.
1982 , vol. 36, # 2 B p. 91 - 99
