diisobutylaluminium hydride in methanol; dichloromethane; toluene T=-78°C; 4 h;

1: With silver nitrate in ethanol; water T=50°C; 0.75 h; 2: With hydrogenchloride; water in ethanol T=20°C;

1: 1-bromo-4-(diethoxymethyl)-2-fluorobenzene With n-butyllithium in tetrahydrofuran; hexanes T=-78°C; 0.666667 h; 2: carbon dioxide in tetrahydrofuran; hexanes 0.5 h; 3: With hydrogenchloride; sodium hydroxide; water more than 3 stages;

1.1: N-bromosuccinmide / dibenzoyl peroxide / tetrachloromethane / 40 h / Reflux 2.1: silver nitrate / ethanol; water / 0.75 h / 50 °C 2.2: 20 °C View Scheme

1: 2-Fluoro-4-formyl Benzoic Acid With sodium hydride in N,N-dimethyl-formamide T=0 - 20°C; 2: methyl iodide in N,N-dimethyl-formamide 2 h;