2-甲氧基-5-(2',3',4'-三甲氧基苯基)环庚三烯酮合成路线 （共 13 条）
反应条件
1.1: hydrogen; platinum(IV) oxide / methanol
2.1: sulfuric acid; sodium nitrite / water / 0 °C
2.2: 55 °C
3.1: potassium carbonate / acetone / 60 °C
4.1: palladium diacetate; triphenylphosphine; tetrabutyl ammonium fluoride / tetrahydrofuran
View Scheme
参考文献
Chang, Dong-Jo; Kim, Wan-Joo
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 14 p. 3121 - 3125
反应条件
1: 61 percent / Et3N / Ambient temperature
2: 1.) ZnCl2, 2.) Pd(Ph3P)4 / 1.) THF, room temperature, 1 h, 2.) room temperature, 1 h
View Scheme
参考文献
Keenan, Richard M.; Kruse, Lawrence I.
Synthetic Communications, 1989 , vol. 19, # 5and6 p. 793 - 798
反应条件
tetrakis(triphenylphosphine) palladium(0); zinc(II) chloride
1.) THF, room temperature, 1 h, 2.) room temperature, 1 h; Yield given. Multistep reaction;
参考文献
Keenan, Richard M.; Kruse, Lawrence I.
Synthetic Communications, 1989 , vol. 19, # 5and6 p. 793 - 798
