5-氯-1-甲基-1H-吲哚-2,3-二酮合成路线 （共 20 条）
反应条件
1: H2SO4 / 80 °C 2: NaH / N,N-dimethyl-acetamide / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 17 p. 2427 - 2430
反应条件
1: (COCl)2 / Ambient temperature 2: i-Pr2NEt / tetrahydrofuran / 1 h / 35 °C 3: Br2 / 2 h / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 10 p. 1619 - 1625
反应条件
1: 5-chloroindolin-2,3-dione With sodium hydride in N,N-dimethyl-formamide; mineral oil Cooling; 2: MeX, X = halide in N,N-dimethyl-formamide; mineral oil
参考文献
Chemistry - A European Journal, , vol. 17, # 27 p. 7409 - 7413
反应条件
potassium hydroxide in ethanol
参考文献
Journal of the Indian Chemical Society, , vol. 59, # 10 p. 1174 - 1176
反应条件
1: potassium carbonate 2: trichloroisocyanuric acid; sulfuric acid View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 11, # 42 p. 7372 - 7386
反应条件
bromine 2 h; Ambient temperature; Yield given;
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 10 p. 1619 - 1625
反应条件
acetic acid in ethanol 4 h; Heating;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 24, p. 280 - 285
反应条件
1: With dihydrogen peroxide; sodium hydroxide in water T=30°C; Cooling with ice; 2: With acetic acid in water pH=5 - 6; Cooling with ice;
参考文献
Wang, Yao; Zhang, Mei; Cao, Shengli; Lin, Huihui; Gao, Man; Li, Zhongfeng
Synthetic Communications, 2012 , vol. 42, # 18 p. 2715 - 2727
反应条件
3-chloro-benzenecarboperoxoic acid in dichloromethane T=20°C;
参考文献
Tojo, Takashi; Spears, Glen W; Tsuji, Kiyoshi; Nishimura, Hiroaki; Ogino, Takashi; Seki, Nobuo; Sugiyama, Aiko; Matsuo, Masaaki
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 17 p. 2427 - 2430
反应条件
acetic acid in ethanol
4 h; Heating;
参考文献
Verma, Rajendra S.; Pandey, Rajnish K.; Kumar, Piyush
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, p. 775 - 777
