1-(2,2-二溴乙烯)-4-甲基苯合成路线 （共 23 条）
反应条件
ethylene glycol dimethyl ether; titanium tetrachloride; magnesium in dichloromethane
T=0 - 25°C; 2.5 h; Inert atmosphere; chemoselective reaction;
参考文献
Bhorge, Yeshwant Ramchandra; Chang, Cheng-Ta; Chang, Su-Haur; Yan, Tu-Hsin
European Journal of Organic Chemistry, 2012 , # 25 p. 4805 - 4810
反应条件
Cu2Cl2; ammonium hydroxide in dimethyl sulfoxide
T=20°C; 4 h;
参考文献
Shastin; Korotchenko; Nenajdenko; Balenkova
Synthesis, 2001 , # 14 p. 2081 - 2084
反应条件
potassium hydroxide in ethanol
T=45 - 55°C; 1 h;
参考文献
Kostikov, R. R.; Krasikov, A. Ya.; Mandel'shtam, T. V.; Kharicheva, E. M.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, # 2 p. 294 - 298
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 2 p. 329 - 333
反应条件
1: 64 percent / 50percent aq. NaOH / triethylbenzylammonium chloride / ethanol / 6 h / 1) 35 - 45 deg C, 6 h, 2) room temperature, 10 h
2: 40 percent / KOH / ethanol / 1 h / 45 - 55 °C
View Scheme
参考文献
Kostikov, R. R.; Krasikov, A. Ya.; Mandel'shtam, T. V.; Kharicheva, E. M.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, # 2 p. 294 - 298
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 2 p. 329 - 333
反应条件
carbon tetrabromide; polystyrene-supported triphenylphosphine in chloroform
T=50°C; 1 h;
参考文献
Hodge, Philip; Khoshdel, Ezzatollah
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 2 p. 195 - 198
反应条件
polystyrene-supported triphenylphosphine in chloroform
T=50°C; 1 h;
参考文献
Hodge, Philip; Khoshdel, Ezzatollah
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 2 p. 195 - 198
反应条件
in dichloromethane
0.5 h; Ambient temperature;
参考文献
Bestmann, Hans Juergen; Frey, Herbert
Liebigs Annalen der Chemie, 1980 , # 12 p. 2061 - 2071
反应条件
1: benzene
2: H2O / benzene / 0.5 h
View Scheme
参考文献
Bestmann, Hans Juergen; Frey, Herbert
Synthesis, 1984 , # 3 p. 243
反应条件
aluminum oxide; potassium fluoride; copper(l) iodide; triphenylphosphine; nickel
0.05 h; microwave irradiation;
参考文献
Yan, Jincan; Wang, Zhiyuan; Wang, Lei
Journal of Chemical Research, 2004 , # 1 p. 71 - 73
反应条件
1: 1,1-dibromo-2-(4-methylphenyl)-1-ethene With n-butyllithium in tetrahydrofuran; hexane
T=-78 - 25°C; 2 h; Inert atmosphere;
2: carbon dioxide in tetrahydrofuran; hexane
T=-60 - 20°C; Inert atmosphere;
参考文献
Zhao, Baoli
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 35 p. 7108 - 7119
