N'-氰基-N-(3-吡啶基)-N''-(T-丁基)胍合成路线 （共 4 条）
参考文献
Leo Pharmaceutical Products Ltd. A/S
Patent: US4057636 A1, 1977 ;
反应条件
1: PPh3, Et3N, CCl4 / CH2Cl2 / 4 h / Heating
2: N-ethyldiisopropylamine / 18 h / 35 °C
View Scheme
参考文献
Manley; Quast
Journal of Medicinal Chemistry, 1992 , vol. 35, # 12 p. 2327 - 2340
反应条件
1: 35 percent / ethanol / 2 h / 20 °C
2: PPh3, Et3N, CCl4 / CH2Cl2 / 4 h / Heating
3: N-ethyldiisopropylamine / 18 h / 35 °C
View Scheme
参考文献
Manley; Quast
Journal of Medicinal Chemistry, 1992 , vol. 35, # 12 p. 2327 - 2340
反应条件
N-ethyl-N,N-diisopropylamine
T=35°C; 18 h; Yield given;
参考文献
Manley; Quast
Journal of Medicinal Chemistry, 1992 , vol. 35, # 12 p. 2327 - 2340
