3,3-二苯基-2-丙烯酸合成路线 （共 82 条）
反应条件
trifluorormethanesulfonic acid
T=25°C; 6 h;
参考文献
Rendy, Rendy; Zhang, Yun; McElrea, Aaron; Gomez, Alma; Klumpp, Douglas A.
Journal of Organic Chemistry, 2004 , vol. 69, # 7 p. 2340 - 2347
反应条件
tert.-butylnitrite; copper(l) chloride in acetonitrile
T=80°C; Reagent/catalystSolvent;
参考文献
Rokade, Balaji V.; Prabhu, Kandikere Ramaiah
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 39 p. 6713 - 6716
反应条件
sodium acetate; acetone; copper dichloride
T=27 - 28°C;
参考文献
Bergmann; Dimant; Japhe
Journal of the American Chemical Society, 1948 , vol. 70, p. 1618
参考文献
Bergmann; Dimant; Japhe
Journal of the American Chemical Society, 1948 , vol. 70, p. 1618
反应条件
(i) SOCl2, (ii) /BRN= 1364011/, Py, benzene; Multistep reaction;
参考文献
Nissan Chem.
Patent: FR2279333DE2519433 , 19761976 ;
Chem.Abstr., 1976 , vol. 85, # 123623
参考文献
Burtner; Cusic
Journal of the American Chemical Society, 1943 , vol. 65, p. 262,263
反应条件
1: With water; sodium hydroxide in ethylene glycol
72 h; Reflux;
2: With hydrogenchloride in water; ethylene glycol
pH=1;
参考文献
ZALICUS PHARMACEUTICALS LTD.; PAJOUHESH , Hassan; DING, Yanbing
Patent: WO2011/26240 A1, 2011 ;
Location in patent: Page/Page column 34 ;
WO 2011/026240 A1
反应条件
sodium hydroxide; carbon monoxide; methyl iodide; N-hexadecyl-N,N,N-trimethylammonium bromide in water; benzene
T=60°C; P=760 Torr; 20 h;
参考文献
Miura, Masahiro; Akase, Fumiaki; Shinohara, Masato; Nomura, Masakatsu
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 1021 - 1026
反应条件
potassium hydroxide in ethanol
T=20°C; 15 h;
参考文献
Groundwater, Paul W.; Garnett, Ian; Morton, Andrew J.; Sharif, Toqir; Coles, Simon J.; Hursthouse, Michael B.; Nyerges, Miklos; Anderson, Rosaleen J.; Bendell, David; McKillop, Alexander; Zhang, Weimin
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 21 p. 2781 - 2787
反应条件
silver(I) acetate; palladium diacetate; acetic acid
T=110°C; Heck reaction; 12 h;
参考文献
Xu, Daichao; Lu, Chunxin; Chen, Wanzhi
Tetrahedron, 2012 , vol. 68, # 5 p. 1466 - 1474
