2-氰基-5-氟苯甲酸甲酯合成路线 （共 4 条）
反应条件
acetyl chloride
T=0°C;
参考文献
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
Patent: WO2008/28688 A2, 2008 ;
Location in patent: Page/Page column 134 ;
参考文献
Bayer Schering Pharma Aktiengesellschaft
Patent: EP1897885 A1, 2008 ;
反应条件
in DMF (N,N-dimethyl-formamide)
1.5 h; Heating / reflux;
参考文献
ASTRAZENECA AB
Patent: WO2005/75424 A1, 2005 ;
Location in patent: Page/Page column 114-115 ;
WO 2005/075424 A1
反应条件
in DMF (N,N-dimethyl-formamide)
T=100°C; 10 - 16 h;
参考文献
Lee, Jaemoon; Zhong, Yong-Li
Patent: US2004/220273 A1, 2004 ;
Location in patent: Page 16 ;
