(Z)-2-乙酰氨基-3-苯基丙烯酸甲酯合成路线 （共 37 条）
反应条件
1,4-dioxane; sodium carbonate
参考文献
Journal of the Chemical Society, , p. 273,276
反应条件
1: aqueous NaOH 3: SOCl2; CHCl3 4: Na2CO3; aqueous dioxane View Scheme
参考文献
Journal of the Chemical Society, , p. 273,276
反应条件
2: SOCl2; CHCl3 3: Na2CO3; aqueous dioxane View Scheme
参考文献
Journal of the Chemical Society, , p. 273,276
反应条件
triethylamine 3 h; Reflux;
参考文献
Zheng, Yunhui; Li, Xuming; Ren, Chengfeng; Zhang-Negrerie, Daisy; Du, Yunfei; Zhao, Kang
Journal of Organic Chemistry, 2012 , vol. 77, # 22 p. 10353 - 10361
参考文献
Helvetica Chimica Acta, , vol. 83, # 1 p. 258 - 277
反应条件
{(1,5-cyclooctadiene)Rh(1,2-bis((2S,5S)-2,5-diethylphospholano)benzene)}triflate; hydrogen in methanol T=20 - 25°C; P=1551.4 Torr;
参考文献
Bunlaksananusorn, Tanasri; Polborn, Kurt; Knochel, Paul
Angewandte Chemie - International Edition, 2003 , vol. 42, # 33 p. 3941 - 3943
反应条件
hydrogen; (S,S)-(-)-1-r,2-c,5-t-triphenylphospholane; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate in methanol T=20°C; P=760 Torr; 0.333333 h;
参考文献
THE PENN STATE RESEARCH FOUNDATION
Patent: EP918781 B1, 2004 ;
Location in patent: Page 10 ;
反应条件
bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; C55H31BF22N2O2P(1-)*C16H36N(1+); hydrogen in dichloromethane T=20°C; P=7500.75 Torr; 1 h; Inert atmosphereSchlenk technique; Reagent/catalystSolvent; enantioselective reaction;
参考文献
Frank, Dominik J.; Franzke, Axel; Pfaltz, Andreas
Chemistry - A European Journal, 2013 , vol. 19, # 7 p. 2405 - 2415
反应条件
bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; (R)-1-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)-4-pentafluorophenylmethylpiperazine; hydrogen in toluene T=20°C; P=7500.75 Torr; 1 h; Inert atmosphereSchlenk technique; Reagent/catalystSolvent; enantioselective reaction;
参考文献
Frank, Dominik J.; Franzke, Axel; Pfaltz, Andreas
Chemistry - A European Journal, 2013 , vol. 19, # 7 p. 2405 - 2415
反应条件
sodium hydroxide Hydrolysis;
参考文献
Holland et al.
Journal of the Chemical Society, 1953 , p. 273,276
