反-1,1,4,4-四甲氧基-2-丁烯合成路线 （共 7 条）
反应条件
bromine; sodium carbonate T=-45 - 20°C; 39 h;
参考文献
DIFFUSION PHARMACEUTICALS LLC
Patent: WO2005/28411 A1, 2005 ;
Location in patent: Page/Page column 26 ;
反应条件
acidic ion exchanger Dowex.(R).50WX4 T=0 - 10°C; 3 - 14 h;
参考文献
US6407291 B1, ;
Page column 5-6 ;
反应条件
lithium diisopropyl amide in tetrahydrofuran T=0°C; 3 h; Title compound not separated from byproducts;
参考文献
Heterocycles, , vol. 23, # 3 p. 653 - 659
反应条件
amberlyst-15 in water; acetone 0.0833333 h;
参考文献
Coppola, Gary M.
Synthesis, 1984 , # 12 p. 1021 - 1023
反应条件
acidic Amberlyst-15 ion exchange resin in water; acetone T=0°C; Elimination; 1 h; Title compound not separated from byproducts;
参考文献
Nadkarni, Durgesh V.; Sayre, Lawrence M.
Chemical Research in Toxicology, 1995 , vol. 8, # 2 p. 284 - 291
反应条件
amberlyst-15 in water; acetone 0.0833333 h;
参考文献
Coppola, Gary M.
Synthesis, 1984 , # 12 p. 1021 - 1023
反应条件
acidic Amberlyst-15 ion exchange resin in water; acetone T=0°C; Elimination; 1 h; Title compound not separated from byproducts;
参考文献
Nadkarni, Durgesh V.; Sayre, Lawrence M.
Chemical Research in Toxicology, 1995 , vol. 8, # 2 p. 284 - 291
