N-(2,6-二甲基苯)甲酰胺合成路线 （共 17 条）
反应条件
triethylamine; trichloromethyl chloroformate in dichloromethane Reflux;
参考文献
Dyadchenko; Belov; Slovokhotov; Banaru; Lemenovskii
Russian Chemical Bulletin, 2010 , vol. 59, # 3 p. 539 - 543
反应条件
dimethylsulfide borane complex in tetrahydrofuran 3 h; Heating; Yield given;
参考文献
Krishnamurthy, S.
Tetrahedron Letters, 1982 , vol. 23, # 33 p. 3315 - 3318
反应条件
1: 100 percent / aq. HCl, NaNO2 / CH2Cl2 / 2 h / 20 - 25 °C 2: 56 percent / 2,4-bis-(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane-2,4-disulfide / 1,2-dimethoxy-ethane / 24 h / Ambient temperature View Scheme
参考文献
Bulletin de la Societe Chimique de France, , vol. 2, # 5-6 p. 204 - 208
反应条件
triethylamine in dichloromethane
cooling;
参考文献
Bowen, Richard J.; Caddy, Judy; Coyanis, Mabel E.; Fernandes, Manuel A.; Layh, Marcus; Linganiso, Linda Z.; Maboya, Winny K.; Omondi, Bernard
Australian Journal of Chemistry, 2005 , vol. 58, # 7 p. 522 - 530
反应条件
hydrogenchloride; sodium nitrite in dichloromethane
T=20 - 25°C; 2 h;
参考文献
Joergensen, Karl Anker; Ghattas, Abdul-Badik; Lawesson, Sven-Olov
Bulletin de la Societe Chimique de France, 1984 , vol. 2, # 5-6 p. 204 - 208
反应条件
1: (i) K2CO3, MeCOEt, (ii) /BRN= 506028/, (iii) LiAlH4, Et2O
View Scheme
参考文献
Barron,D.I. et al.
J. Med. Chem., 1963 , vol. 6, p. 705 - 711
反应条件
1.1: triethylamine; trichlorophosphate / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere
2.1: palladium diacetate; caesium carbonate; di-(1-adamantyl)-n-butylphosphine / toluene / 20 - 100 °C / Inert atmosphere
2.2: 4 h / 100 °C / Inert atmosphere
View Scheme
参考文献
Nanjo, Takeshi; Tsukano, Chihiro; Takemoto, Yoshiji
Organic Letters, 2012 , vol. 14, # 16 p. 4270 - 4273
