1: 2-ethylacetoacetic acid ethyl ester With lithium hexamethyldisilazane in tetrahydrofuran T=-78°C; 0.5 h; 2: formaldehyd in tetrahydrofuran T=-78 - 20°C; Further stages.;
参考文献
Beddow, James E.; Davies, Stephen G.; Ling, Kenneth B.; Roberts, Paul M.; Russell, Angela J.; Smith, Andrew D.; Thomson, James E.
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 17 p. 2812 - 2825
1: 2-ethylacetoacetic acid ethyl ester With (DL)-norvaline in dichloromethane 0.0833333 h; 2: 2,2-dibromo-5,5-dimethyl cyclohexane-1,3-dione With dipyridinium dichromate in dichloromethane 2 h; Cooling with ice; optical yield given as percent eeenantioselective reaction;
参考文献
Goswami, Papori; Baruah, Abhilasha; Das, Babulal
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 10 p. 1483 - 1487
