1-苄基-3-甲基氨基哌啶合成路线 (共 4 条)
反应条件
1: 85 percent / CH2Cl2 2: 90 percent / H2 / 10percent Pd/C / ethanol / Ambient temperature 3: 80 percent / 1 h / 100 °C 4: 87 percent / HCl / diethyl ether / Ambient temperature View Scheme
参考文献
Barlocco, Daniela; Villa, Stefania; Fratta, Walter; Fadda, Paola; Colombo, Diego; Toma, Lucio
Tetrahedron, 1995 , vol. 51, # 42 p. 11547 - 11556
反应条件
1: 85 percent / CH2Cl2 2: 90 percent / H2 / 10percent Pd/C / ethanol / Ambient temperature View Scheme
参考文献
Barlocco, Daniela; Villa, Stefania; Fratta, Walter; Fadda, Paola; Colombo, Diego; Toma, Lucio
Tetrahedron, 1995 , vol. 51, # 42 p. 11547 - 11556
反应条件
hydrogen; methylamine in ethanol
参考文献
SmithKline Corporation
Patent: US3980788 A1, 1976 ;
反应条件
sodium tetrahydroborate in methanol; water
1 h; Ambient temperature;
参考文献
Barlocco, Daniela; Villa, Stefania; Fratta, Walter; Fadda, Paola; Colombo, Diego; Toma, Lucio
Tetrahedron, 1995 , vol. 51, # 42 p. 11547 - 11556