(4aS,6R,8aS)-11-甲基-5,6,9,10,11,12-六氢-4aH-[1]苯并呋喃并[3a,3,2-ef][2]苯并氮杂卓-3,6-二醇合成路线 （共 4 条）
→
60755-80-8(4aS,6R,8aS)-11-甲基-5,6,9,10,11,12-六氢-4aH-[1]苯并呋喃并[3a,3,2-ef][2]苯并氮杂卓-3,6-二醇
反应条件
L-Selectridereg; in tetrahydrofuran 20 h; Heating;
参考文献
Mary, Aude; Renko, Dolor Zafiarisoa; Guillou, Catherine; Thal, Claude
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 10 p. 1835 - 1850
→
60755-80-8(4aS,6R,8aS)-11-甲基-5,6,9,10,11,12-六氢-4aH-[1]苯并呋喃并[3a,3,2-ef][2]苯并氮杂卓-3,6-二醇
反应条件
L-Selectridereg; in tetrahydrofuran T=65°C; 24 h;
参考文献
Rouleau, Julien; Guillou, Catherine
Journal of Labelled Compounds and Radiopharmaceuticals, 2008 , vol. 51, # 5 p. 236 - 238
60755-80-8(4aS,6R,8aS)-11-甲基-5,6,9,10,11,12-六氢-4aH-[1]苯并呋喃并[3a,3,2-ef][2]苯并氮杂卓-3,6-二醇
→
反应条件
in diethyl ether; dimethyl sulfoxide 48 h; Ambient temperature;
参考文献
Kobayashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1976 , vol. 24, p. 1537 - 1543
60755-80-8(4aS,6R,8aS)-11-甲基-5,6,9,10,11,12-六氢-4aH-[1]苯并呋喃并[3a,3,2-ef][2]苯并氮杂卓-3,6-二醇
→
反应条件
1: 11 mg / MCPBA / CHCl3 / 0.5 h / Ambient temperature 2: 2.7 mg / methanol; diethyl ether / 48 h / Ambient temperature View Scheme
参考文献
Kobayashi, Shigeru; Satoh, Kimihito; Numata, Atsushi; Shingu, Tetsuro; Kihara, Masaru
Phytochemistry (Elsevier), 1991 , vol. 30, # 2 p. 675 - 677
