1,3-二甲基-2-碘苯合成路线 （共 73 条）
反应条件
copper
T=240 - 265°C;
参考文献
Carlin
Journal of the American Chemical Society, 1945 , vol. 67, p. 928,931
反应条件
palladium diacetate; triphenylphosphine; cesium fluoride in ethylene glycol dimethyl ether
T=70°C; Suzuki coupling; 6 h;
参考文献
Castanet, Anne-Sophie; Colobert, Francoise; Broutin, Pierre-Emmanuel; Obringer, Michel
Tetrahedron Asymmetry, 2002 , vol. 13, # 6 p. 659 - 665
反应条件
tetrabutyl ammonium fluoride in water; toluene
T=100°C; Hiyama Coupling; 20 h;
参考文献
Diebold, Carine; Derible, Antoine; Becht, Jean-Michel; Le Drian, Claude
Tetrahedron, 2013 , vol. 69, # 1 p. 264 - 267
反应条件
dpca; potassium carbonate; palladium dichloride in water; dimethyl sulfoxide
T=50°C; 13 h;
参考文献
Nakao, Yoshiaki; Imanaka, Hidekazu; Sahoo, Akhila K.; Yada, Akira; Hiyama, Tamejiro
Journal of the American Chemical Society, 2005 , vol. 127, # 19 p. 6952 - 6953
反应条件
disodium hydrogenphosphate; Pd(OAc)2(2-amino-4,6-dihydroxypyrimidine disodium salt)2 in water; N,N-dimethyl-formamide
T=120°C; Suzuki-Miyaura coupling; 0.166667 h; Microwave irradiation;
参考文献
Chalker, Justin M.; Wood, Charlotte S. C.; Davis, Benjamin G.
Journal of the American Chemical Society, 2009 , vol. 131, # 45 p. 16346 - 16347
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate in chlorobenzene
T=80°C; Suzuki cross-coupling; P=760.051 Torr; 24 h; Inert atmosphere;
参考文献
O'Keefe, B. Michael; Simmons, Nicholas; Martin, Stephen F.
Tetrahedron, 2011 , vol. 67, # 24 p. 4344 - 4351
反应条件
10 Pd/C; tetrabutyl ammonium fluoride in 1-methyl-pyrrolidin-2-one
T=140°C; 24 h; Inert atmosphere;
参考文献
Monguchi, Yasunari; Hattori, Tomohiro; Miyamoto, Yasuhiro; Yanase, Takayoshi; Sawama, Yoshinari; Sajiki, Hironao
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 13 p. 2561 - 2567
反应条件
in tetrahydrofuran; toluene
T=110°C; 24 h; Inert atmosphere;
参考文献
Shirakawa, Eiji; Hayashi, Yumi; Itoh, Ken-Ichi; Watabe, Ryo; Uchiyama, Nanase; Konagaya, Wataru; Masui, Seiji; Hayashi, Tamio
Angewandte Chemie - International Edition, 2012 , vol. 51, # 1 p. 218 - 221
反应条件
C27H38N4(2+)*2I(1-); potassium tert-butylate
T=130°C; 22 h; Reagent/catalyst;
参考文献
Zhou, Shengze; Anderson, Greg M.; Mondal, Bhaskar; Doni, Eswararao; Ironmonger, Vicki; Kranz, Michael; Tuttle, Tell; Murphy, John A.
Chemical Science, 2014 , vol. 5, # 2 p. 476 - 482
反应条件
copper(l) iodide; 1,10-phenanthroline in dimethyl sulfoxide
T=60°C; 16 h; Inert atmosphere;
参考文献
Knauber, Thomas; Arikan, Fatih; Roeschenthaler, Gerd-Volker; Goossen, Lukas J.
Chemistry - A European Journal, 2011 , vol. 17, # 9 p. 2689 - 2697
