(S)-(-)-乙基白氨酸酯合成路线 （共 11 条）
反应条件
hydrogen; platinum(IV) oxide in ethanol
T=20°C; Hydrogenation; 16 h;
参考文献
Evans, David A.; Tregay, Steven W.; Burgey, Christopher S.; Paras, Nick A.; Vojkovsky, Tomas
Journal of the American Chemical Society, 2000 , vol. 122, # 33 p. 7936 - 7943
反应条件
1: aq. NaNO2, H2SO4
2: aq. HCl / toluene
View Scheme
参考文献
Mori
Tetrahedron, 1976 , vol. 32, # 10 p. 1101 - 1106
反应条件
potassium 9-O-(1,2:5,6-di-O-isopropylidene-α-D-glucofuranosyl)-9-boratabicyclolt;3.3.1gt;nonane in tetrahydrofuran
T=-78°C; 6 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Brown, Herbert C.; Cho, Byung Tae; Park, Won Suh
Journal of Organic Chemistry, 1988 , vol. 53, # 6 p. 1231 - 1238
反应条件
hydrogenchloride in toluene
参考文献
Janssen, Henk M.; Peeters, Emiel; Van Zundert, Marga F.; Van Genderen, Marcel H.P.; Meijer
Angewandte Chemie (International Edition in English), 1997 , vol. 36, # 1-2 p. 122 - 125
反应条件
hydrogenchloride
T=90°C; Hydrolysis; 8 h;
参考文献
Effenberger, Franz; Roos, Juergen
Tetrahedron Asymmetry, 2000 , vol. 11, # 5 p. 1085 - 1095
反应条件
1: dimethylformamide
2: HCl / 8 h / 90 °C
View Scheme
参考文献
Effenberger, Franz; Roos, Juergen
Tetrahedron Asymmetry, 2000 , vol. 11, # 5 p. 1085 - 1095
反应条件
1: pyridine
2: dimethylformamide
3: HCl / 8 h / 90 °C
View Scheme
参考文献
Effenberger, Franz; Roos, Juergen
Tetrahedron Asymmetry, 2000 , vol. 11, # 5 p. 1085 - 1095
反应条件
hydrogenchloride
T=90°C; Hydrolysis; 8 h;
参考文献
Effenberger, Franz; Roos, Juergen
Tetrahedron Asymmetry, 2000 , vol. 11, # 5 p. 1085 - 1095
反应条件
1: t-BuOK / tetrahydrofuran / 0.25 h / 0 °C
2: aq. AD-mix β, CH3SO2NH2 / 2-methyl-propan-2-ol / 0 °C
View Scheme
参考文献
Kirschning, Andreas; Draeger, Gerald; Jung, Alexander
Angewandte Chemie (International Edition in English), 1997 , vol. 36, # 3 p. 253 - 255
参考文献
Bartlett; Kuna; Levene
Journal of Biological Chemistry, 1937 , vol. 118, p. 515
