2-[(4-甲氧基苄基)氨基]乙酸乙酯合成路线 （共 6 条）
反应条件
sodium cyanoborohydride in ethanol T=20°C; 24 h;
参考文献
Lopez-Cobenas, Alberto; Cledera, Pilar; Sanchez, J. Domingo; Lopez-Alvarado, Pilar; Ramos, M. Teresa; Avendano, Carmen; Menendez, J. Carlos
Synthesis, 2005 , # 19 art. no. C06905SS, p. 3412 - 3422
反应条件
1: With sodium tetrahydroborate in water T=0 - 20°C; 1 h; 2: With potassium carbonate; acetic acid pH=8 - 9;
参考文献
SCHERING CORPORATION
Patent: US2003/232987 A1, 2003 ;
Location in patent: Page 10 ;
反应条件
triethylamine in tetrahydrofuran 12 h; Ambient temperature;
参考文献
Arcelli, Antonio; Balducci, Daniele; Grandi, Alessandro; Porzi, Gianni; Sandri, Monica; Sandri, Sergio
Monatshefte fur Chemie, 2004 , vol. 135, # 8 p. 951 - 958
参考文献
Synthesis, , # 19 art. no. C06905SS, p. 3412 - 3422
反应条件
sodium tetrahydroborate
参考文献
Bulletin of the Chemical Society of Japan, , vol. 62, # 6 p. 1960 - 1968
反应条件
1: Carbamonitrile; orthoformic acid triethyl ester 2 h; Reflux;
2: 3-N-(p-methoxybenzyl)glycine ethyl ester in diethyl ether
T=20°C; 2 h;
3: With sodium ethanolate in ethanol
T=20°C; 1 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; SIMONEAU, Bruno; DEROY, Patrick; FADER, Lee; FAUCHER, Anne-Marie; GAGNON, Alexandre; GRAND-MAITRE, Chantal; KAWAI, Steven; LANDRY, Serge; MERCIER, Jean-Francois; RANCOURT, Jean
Patent: WO2011/100838 A1, 2011 ;
Location in patent: Page/Page column 55; 56 ;
