1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran T=0 - 20°C; Alkylation;

sodium hydroxide in N,N-dimethyl-formamide 2 h; Ambient temperature;

1: 1H-1,2,4-triazol With sodium methylate in methanol T=-40°C; 2: 1-iodo-butane in methanol Further stages.;

T=100°C; 20 h;

lithium hydroxide; tetrabutylammomium bromide 24 h; Ambient temperaturealso benzotriazole; other alkyl halides; var. base as reagents; also reactions in the absence of base; var. temperatures and reaction time; also with conventional heating or microwave heating instead of phase transfer catalysis; Product distribution;