反应条件
1: 2-chloro-4-phenyl-1-buten-3-yne With n-butyllithium; diisopropylamine in tetrahydrofuran; hexane
T=-78 - -30°C; 1 h;
2: With zinc dibromide in tetrahydrofuran; hexane
T=-30 - 0°C; 0.5 h;
3: benzyl bromide With [Pd{bis[2-(diphenylphosphino)phenyl] ether}Cl2] in tetrahydrofuran; hexane
T=23°C; 3 h;
参考文献
Qian, Mingxing; Negishi, Ei-Ichi
Tetrahedron Letters, 2005 , vol. 46, # 16 p. 2927 - 2930