反应条件
1: 2-(2-propynyloxy)-tetrahydro-2H-pyran With n-butyllithium; N,N,N',N,-tetramethylethylenediamine in tetrahydrofuran
T=-78 - 20°C; 1 h; Inert atmosphere;
2: 5-methyl-1-hexyl bromide With potassium iodide in tetrahydrofuran
T=80°C; 8 h; Inert atmosphere;
参考文献
Yu, Yang; Plettner, Erika
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 7 p. 1811 - 1822
