ammonium chloride in tetrahydrofuran; methanol; water
To a stirred soln. of Me3SnCu*Me2S in THF (Ar, -78°C) was added sequentially a THF soln. of the 1-alkyne. The mixt. was stirred (6h). CH3OH, satd. aq. NH4Cl and ether were added; allowed to warm to room temp.; The org. phase was washed (satd. aq. NH4Cl) and dried (MgSO4). Removal of the solvent; flash chromy. (silica gel) provided 3-tetrahydropyranyloxy-2-trimethylstannylpropene and (E)-3-tetrahydropyranyloxy-1-trimethylstannylpropene.;
参考文献
Piers, Edward; Chong, J. Michael
Canadian Journal of Chemistry, 1988 , vol. 66, p. 1425 - 1429