1: 82 percent / molecular sieves 4 Angstroem / Amberlite IR 120-plus / benzene / Heating 2: K2CO3 / Bu4NHSO4 / acetone / 24 h / Heating 3: TsOH / methanol; H2O / 16 h / Ambient temperature 4: 91 percent / K2CO3 / acetone / 15 h / Heating 5: 96 percent / H2 / 10percent Pd/C / tetrahydrofuran / 6 h / Ambient temperature 6: 92 percent / K2(SO3)2NO, KH2SO4 / benzene; H2O / 3 h / Ambient temperature View Scheme

potassium hydroxide beim Schmelzen;

sodium hydroxide T=70 - 80°C;

sodium hydroxide; ethanol T=10°C;

T=10°C;

1: 82 percent / molecular sieves 4 Angstroem / Amberlite IR 120-plus / benzene / Heating 2: K2CO3 / Bu4NHSO4 / acetone / 24 h / Heating 3: TsOH / methanol; H2O / 16 h / Ambient temperature 4: 91 percent / K2CO3 / acetone / 15 h / Heating 5: 96 percent / H2 / 10percent Pd/C / tetrahydrofuran / 6 h / Ambient temperature View Scheme

hydrogenchloride; diethyl ether und Erwaermen des Reaktionsprodukts mit Wasser;

1: 82 percent / molecular sieves 4 Angstroem / Amberlite IR 120-plus / benzene / Heating 2: K2CO3 / Bu4NHSO4 / acetone / 24 h / Heating 3: TsOH / methanol; H2O / 16 h / Ambient temperature 4: 91 percent / K2CO3 / acetone / 15 h / Heating 5: 96 percent / H2 / 10percent Pd/C / tetrahydrofuran / 6 h / Ambient temperature 6: 92 percent / K2(SO3)2NO, KH2SO4 / benzene; H2O / 3 h / Ambient temperature 7: 100 percent / CH2Cl2 / 96 h / Ambient temperature 8: 1.) KOBu-t / 1.) Et2O, -40 deg C, 30 min, 2.) Et2O, -70 deg C to room temp. 9: 100 percent / 3 h / 80 °C / 7.5 Torr View Scheme