(+/-)-N-(亚苄基)丙氨酸乙酯合成路线 （共 7 条）
反应条件
water; chymotrypsin in acetonitrile 108 h; Yield given. Title compound not separated from byproducts;
参考文献
Parmar, Virinder S.; Singh, Amarjit; Bisht, Kirpal S.; Kumar, Naresh; Belokon; Kochetkov; Ikonnikov; Orlova; Tararov; Saveleva
Journal of Organic Chemistry, 1996 , vol. 61, # 4 p. 1223 - 1226
反应条件
water; chymotrypsin in acetonitrile 108 h; Yield given. Title compound not separated from byproducts;
参考文献
Parmar, Virinder S.; Singh, Amarjit; Bisht, Kirpal S.; Kumar, Naresh; Belokon; Kochetkov; Ikonnikov; Orlova; Tararov; Saveleva
Journal of Organic Chemistry, 1996 , vol. 61, # 4 p. 1223 - 1226
反应条件
Yield given. Multistep reaction;
参考文献
Calcagni, Anna; Rossi, Domenico; Lucente, Gino
Synthesis, 1981 , # 6 p. 445 - 447
反应条件
triethylamine in dichloromethane
T=0 - 25°C; 5 h; Product distribution / selectivity;
参考文献
BASF SE
Patent: US2011/144336 A1, 2011 ;
Location in patent: Page/Page column 7 ;
参考文献
Szarvasi,E. et al.
European Journal of Medicinal Chemistry, 1976 , vol. 11, p. 115 - 124
反应条件
Yield given. Multistep reaction;
参考文献
Calcagni, Anna; Rossi, Domenico; Lucente, Gino
Synthesis, 1981 , # 6 p. 445 - 447
反应条件
1: ethyl (RS)-2-(benzylideneamino)propanoate With n-butyllithium; diisopropylamine in tetrahydrofuran; hexane
T=-60°C; 1.33333 h; Inert atmosphere;
2: benzyl bromide in tetrahydrofuran; hexane
T=-60 - 15°C; 1.83333 h; Inert atmosphere; Product distribution / selectivity;
参考文献
BASF SE
Patent: US2011/144336 A1, 2011 ;
Location in patent: Page/Page column 7 ;
