2-苯基-5,6-二氢吡唑并[5,1-a]异喹啉合成路线 （共 13 条）
反应条件
oxygen in chloroform
T=50°C; P=760.051 Torr; 48 h;
参考文献
Ortega, Heriberto; Ahmed, Sara; Alper, Howard
Synthesis, 2007 , # 23 p. 3683 - 3691
反应条件
sulfuric acid in ethanol
11 h; Heating;
参考文献
Toja; Omodei-Sale; Cattaneo; Galliani
European Journal of Medicinal Chemistry, 1982 , vol. 17, # 3 p. 223 - 227
反应条件
magnesium in methanol
T=0 - 20°C; 1 h; Inert atmosphere;
参考文献
Kawai, Hiroyuki; Yuan, Zhe; Tokunaga, Etsuko; Shibata, Norio
Organic Letters, 2012 , vol. 14, # 20 p. 5330 - 5333,4
反应条件
oxygen in chloroform
T=50°C; P=760.051 Torr; 24 h; Title compound not separated from byproducts.;
参考文献
Ortega, Heriberto; Ahmed, Sara; Alper, Howard
Synthesis, 2007 , # 23 p. 3683 - 3691
反应条件
1: 20.2 g / p-toluenesulfonic acid / benzene / 1 h / Heating
2: 18.3 g / potassium t-butoxide / 2-methyl-propan-2-ol / 5 h / Heating
3: 87 percent / 98percent H2SO4 / ethanol / 11 h / Heating
View Scheme
参考文献
Toja; Omodei-Sale; Cattaneo; Galliani
European Journal of Medicinal Chemistry, 1982 , vol. 17, # 3 p. 223 - 227
反应条件
1: 20.2 g / p-toluenesulfonic acid / benzene / 1 h / Heating
2: 18.3 g / potassium t-butoxide / 2-methyl-propan-2-ol / 5 h / Heating
3: 87 percent / 98percent H2SO4 / ethanol / 11 h / Heating
View Scheme
参考文献
Toja; Omodei-Sale; Cattaneo; Galliani
European Journal of Medicinal Chemistry, 1982 , vol. 17, # 3 p. 223 - 227
反应条件
oxygen; sodium hydrogencarbonate
T=50°C; P=760.051 Torr; 33 h;
参考文献
Ortega, Heriberto; Ahmed, Sara; Alper, Howard
Synthesis, 2007 , # 23 p. 3683 - 3691
反应条件
1.1: dichloromethane / 1 h / 20 °C
1.2: 1 h
2.1: magnesium / methanol / 1 h / 0 - 20 °C / |Inert atmosphere
View Scheme
参考文献
Kawai, Hiroyuki; Yuan, Zhe; Tokunaga, Etsuko; Shibata, Norio
Organic Letters, 2012 , vol. 14, # 20 p. 5330 - 5333,4
反应条件
1: 18.3 g / potassium t-butoxide / 2-methyl-propan-2-ol / 5 h / Heating
2: 87 percent / 98percent H2SO4 / ethanol / 11 h / Heating
View Scheme
参考文献
Toja; Omodei-Sale; Cattaneo; Galliani
European Journal of Medicinal Chemistry, 1982 , vol. 17, # 3 p. 223 - 227
参考文献
Ortega, Heriberto; Ahmed, Sara; Alper, Howard
Synthesis, 2007 , # 23 p. 3683 - 3691
