2-苯基吡唑并[5,1-a]异喹啉合成路线 （共 17 条）
反应条件
1: 33 percent / toluene / 18 h / 105 °C
2: 57percent hydroiodic acid / 3 h / Heating
View Scheme
参考文献
Sundberg, Richard J.; Ellis, James E.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 573 - 576
反应条件
1: 60 percent / K2CO3 / CH2Cl2 / 12 h
2: 33 percent / toluene / 18 h / 105 °C
3: 57percent hydroiodic acid / 3 h / Heating
View Scheme
参考文献
Sundberg, Richard J.; Ellis, James E.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 573 - 576
反应条件
1: 33 percent / toluene / 18 h / 105 °C
2: 57percent hydroiodic acid / 3 h / Heating
View Scheme
参考文献
Sundberg, Richard J.; Ellis, James E.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 573 - 576
反应条件
1: 39 percent / NH2OH*HCl, NaOAc / methanol; H2O / 1 h / Heating
2: 66 percent / O-mesitylsulphonylhydroxylamine / CHCl3 / 1 h / 25 °C
View Scheme
参考文献
Gnichtel, Horst; Moeller, Bernd
Liebigs Annalen der Chemie, 1981 , # 10 p. 1751 - 1759
反应条件
1.1: O-(2,4-dinitro-phenyl)-hydroxylamine / tetrahydrofuran; water / 16 h / 40 °C / Inert atmosphere
2.1: tetrahydrofuran; water / 0.5 h / Inert atmosphere
2.2: Inert atmosphere
3.1: palladium bromide; tris(4-methoxyphenyl)-phosphine; silver benzoate / 1,4-dioxane / 16 h / 125 °C / Inert atmosphere
View Scheme
参考文献
Mousseau, James J.; Bull, James A.; Ladd, Carolyn L.; Fortier, Angelique; Sustac Roman, Daniela; Charette, Andre B.
Journal of Organic Chemistry, 2011 , vol. 76, # 20 p. 8243 - 8261
反应条件
hydrogen iodide
3 h; Heating;
参考文献
Sundberg, Richard J.; Ellis, James E.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 573 - 576
反应条件
O-(2,4,6-trimethylbenzenesulfonyl)hydroxylamine; potassium carbonate
2.) DMF, r.t.; Yield given. Multistep reaction;
参考文献
Tsuchiya, Takashi; Sashida, Haruki
Journal of the Chemical Society, Chemical Communications, 1980 , # 23 p. 1109 - 1110
