2-甲基-1-哌啶-2-丙胺合成路线 （共 3 条）
反应条件
1: K2CO3, Cu powder / 48 h / 160 °C 2: CH2Cl2 View Scheme
参考文献
Geiger; Wollweber
European Journal of Medicinal Chemistry, 1982 , vol. 17, # 3 p. 207 - 215
反应条件
hydrogen; nickel in ethanol
T=30 - 50°C; P=36775.4 Torr;
参考文献
Geiger; Wollweber
European Journal of Medicinal Chemistry, 1982 , vol. 17, # 3 p. 207 - 215
反应条件
1: in tetrahydrofuran; diethyl ether
T=100°C; Double Grignard addition; 0.166667 h; Microwave irradiation;
2: With titanium(IV) isopropylate in tetrahydrofuran; diethyl ether
T=50°C; Double Grignard addition; 1 h; Microwave irradiation;
参考文献
Wang, Ruifang; Gregg, Brian T.; Zhang, Wei; Golden, Kathryn C.; Quinn, John F.; Cui, Peng; Tymoshenko, Dmytro O.
Tetrahedron Letters, 2009 , vol. 50, # 50 p. 7070 - 7073
