2-苯基-1-[4-(三氟甲基)苯基]-乙酮合成路线 （共 12 条）
反应条件
1: With sodium hydrogencarbonate; bis(η3-allyl-μ-chloropalladium(II)); Tedicyp in N,N-dimethyl-formamide T=150°C; Heck reaction; 20 h; 2: With hydrogenchloride in tetrahydrofuran T=25°C; Further stages.;
参考文献
Battace, Ahmed; Feuerstein, Marie; Lemhadri, Mhamed; Zair, Touriya; Doucet, Henri; Santelli, Maurice
European Journal of Organic Chemistry, 2007 , # 19 p. 3122 - 3132
反应条件
scandium tris(trifluoromethanesulfonate) in toluene T=-78°C; 0.166667 h; Inert atmosphere;
参考文献
Wommack, Andrew J.; Moebius, David C.; Travis, Austin L.; Kingsbury, Jason S.
Organic Letters, 2009 , vol. 11, # 15 p. 3202 - 3205
反应条件
palladium diacetate; 1,4-di(diphenylphosphino)-butane in tetrahydrofuran T=90°C; P=1500.15 Torr; 1 h; Sealed tubeMicrowave irradiation; chemoselective reaction;
参考文献
Motwani, Hitesh V.; Larhed, Mats
European Journal of Organic Chemistry, 2013 , # 22 p. 4729 - 4733
反应条件
trans-di(μ-acetato)bis[o-(di-o-tolylphosphino)benzyl]dipalladium(II); 1,8-diazabicyclo[5.4.0]undec-7-ene; [(t-Bu)3PH]BF4 in tetrahydrofuran T=120°C; P=2250.23 Torr; 0.5 h; Microwave irradiationSealed tube; chemoselective reaction;
参考文献
Motwani, Hitesh V.; Larhed, Mats
European Journal of Organic Chemistry, 2013 , # 22 p. 4729 - 4733
反应条件
3,4-dmtz iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile T=20°C; 0.0833333 h; Inert atmosphere;
参考文献
Lin, Lu; Li, Yi; Du, Wenting; Deng, Wei-Ping
Tetrahedron Letters, 2010 , vol. 51, # 27 p. 3571 - 3574
反应条件
1: 85 percent / acetic acid 2: sodium tert-butoxide / Pd2(dba)3; bis(2-diphenylphosphinophenyl)ether / dioxane / 24 h / 70 °C 3: 106 mg / aq. HCl / tetrahydrofuran; methanol / 16 h / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 128, # 46 p. 14800 - 14801
反应条件
palladium diacetate; 1,4-di(diphenylphosphino)-butane; zinc in 1,4-dioxane T=100°C; Negishi coupling reaction; P=7500.75 Torr; 16 h; Inert atmosphereAutoclave;
参考文献
Wu, Xiao-Feng; Schranck, Johannes; Neumann, Helfried; Beller, Matthias
Chemistry - An Asian Journal, 2012 , vol. 7, # 1 p. 40 - 44
反应条件
[CpFe(CO)2(THF)][BF4] in dichloromethane T=20°C; Cycloaddition; insertion; 12.5 h;
参考文献
Tetrahedron, , vol. 54, # 3-4 p. 349 - 358
反应条件
1: NaHCO3; Tedicyp / [PdCl(C3H5)]2 / dimethylformamide / 20 h / 150 °C 2: 62 percent / HCl / tetrahydrofuran; H2O / 25 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 4 p. 459 - 462
反应条件
1: NaHCO3; Tedicyp / [PdCl(C3H5)]2 / dimethylformamide / 20 h / 150 °C 2: 62 percent / HCl / tetrahydrofuran; H2O / 25 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 47, # 4 p. 459 - 462
