N-(3-氨基丙基)苯甲酰胺合成路线 (共 14 条)
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal in methanol; ethanol
T=80°C; P=51714.8 Torr; Yield given;
参考文献
Manoury; Binet; Dumas; Lefevre-Borg; Cavero
Journal of Medicinal Chemistry, 1986 , vol. 29, # 1 p. 19 - 25
反应条件
hydrogenchloride; sodium hydroxide in water
参考文献
Coleman, Patrick L.; Crooks, Stephen L.; Griesgraber, George W.; Lindstrom, Kyle J.; Merrill, Bryon A.; Rice, Michael J.
Patent: US2003/144283 A1, 2003 ;
US 20030144283 A1
反应条件
in ethanol; water
T=20°C; 6.16667 h;
参考文献
Verma, Sanjeev K.; Acharya; Kaushik
Organic Letters, 2010 , vol. 12, # 19 p. 4232 - 4235
反应条件
in methanol
T=25°C; 2 h;
参考文献
Maurya, Ram Awatar; Hoang, Phan Huy; Kim, Dong-Pyo
Lab on a Chip - Miniaturisation for Chemistry and Biology, 2012 , vol. 12, # 1 p. 65 - 68
反应条件
1: 1,3-diamino-propane With 9-borabicyclo[3.3.1]nonane dimer in tetrahydrofuran; hexane
T=20°C; 1 h;
2: benzoyl chloride in tetrahydrofuran; hexane
T=20°C; 2 h;
参考文献
Zhang, Zhongxing; Yin, Zhiwei; Meanwell, Nicholas A.; Kadow, John F.; Wang, Tao
Organic Letters, 2003 , vol. 5, # 19 p. 3399 - 3402
反应条件
in ethanol
60 h; Heating;
参考文献
Anker; Testa; Van de Waterbeemd; et al.
Helvetica Chimica Acta, 1983 , vol. 66, # 2 p. 542 - 556
反应条件
in dichloromethane
T=-80°C;
参考文献
Galbraith, Stuart G.; Wang, Qiang; Li, Li; Blake, Alexanders; Wilson, Claire; Collinson, Simon R.; Lindoy, Leonard F.; Plieger, Paul G.; Schroeder, Martin; Tasker, Peter A.
Chemistry - A European Journal, 2007 , vol. 13, # 21 p. 6090 - 6107
参考文献
Aspinall
Journal of the American Chemical Society, 1940 , vol. 62, p. 2160
反应条件
in dichloromethane
T=-78 - 20°C; 15 h; Inert atmosphere;
参考文献
Kwie, Franciane Ho A.; Briet, Martine; Soupaya, David; Hoffmann, Pascal; Maturano, Marie; Rodriguez, Frederic; Blonski, Casimir; Lherbet, Christian; Baudoin-Dehoux, Cecile
Chemical Biology and Drug Design, 2011 , vol. 77, # 1 p. 86 - 92
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane
参考文献
Loughlin, Wendy A.; Jenkins, Ian D.; Petersson, Maria J.
Journal of Organic Chemistry, 2013 , vol. 78, # 14 p. 7356 - 7361