2-甲基-1-苯基-1-丙醇合成路线 (共 136 条)
反应条件
2,4-dinitrobenzenesulfonic acid hydrate T=80°C; Ritter reaction; 15 h;
参考文献
Sanz, Roberto; Martinez, Alberto; Guilarte, Veronica; Alvarez-Gutierrez, Julia M.; Rodriguez, Felix
European Journal of Organic Chemistry, 2007 , # 28 p. 4642 - 4645
反应条件
perchloric acid in 1,4-dioxane T=62°C; 100 h;
参考文献
Bulletin de la Societe Chimique de France, , p. 3307 - 3314
反应条件
(1S,2R)-(+)-erythro-2-amino-1,2-diphenylethanol; benzoic acid in hexane
T=20°C; 12 h;
参考文献
Kodama, Koichi; Kobayashi, Yuka; Saigo, Kazuhiko
Chemistry - A European Journal, 2007 , vol. 13, # 7 p. 2144 - 2152
反应条件
chiral 2-(3',5'-di-tert-butylphenyl)-4,4,8-trimethyl-2-phosphabicyclolt;3.3.0gt;octane in n-heptane
T=-40°C; 42 h; Title compound not separated from byproducts;
参考文献
MacKay, James A.; Vedejs, Edwin
Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6934 - 6937
反应条件
1: With MnIII(L-5-t-Bu)(Cl); 1-butyl-2,6-dimethyl-pyridinium; bromide in dichloromethane; water
T=20°C;
2: With [bis(acetoxy)iodo]benzene in dichloromethane; water
T=20°C; 0.1 h;
参考文献
Zhang, Yuecheng; Zhou, Qiao; Ma, Wenchan; Zhao, Jiquan
Catalysis Communications, 2014 , vol. 45, p. 114 - 117
反应条件
(1R,2R,4S,5S)-4,8,8-triMe-2-Ph-2-phosphabicyclo[3.3.0]octane in toluene
T=20°C; 1 h; Title compound not separated from byproducts;
参考文献
MacKay, James A.; Vedejs, Edwin
Journal of Organic Chemistry, 2006 , vol. 71, # 2 p. 498 - 503
反应条件
Birman's catalyst; nicotinic anhydride in dichloromethane
T=0°C; 12 h; Resolution of racemate; optical yield given as percent eeenantioselective reaction;
参考文献
Shiina, Isamu; Nakata, Kenya; Ono, Keisuke; Mukaiyama, Teruaki
Helvetica Chimica Acta, 2012 , vol. 95, # 10 p. 1891 - 1911,21
Title/Abstract Full Text Show Details
Shiina, Isamu; Nakata, Kenya; Ono, Keisuke; Mukaiyama, Teruaki
Helvetica Chimica Acta, 2012 , vol. 95, # 10 p. 1891 - 1911
反应条件
(R)-5-CF3-2-Ph-2,3-dihydroimidazo[1,2-a]pyridine; N-ethyl-N,N-diisopropylamine in chloroform
T=0°C; 30 h; Title compound not separated from byproducts;
参考文献
Gleeson, Oliver; Gun'Ko, Yurii K.; Connon, Stephen J.
Synlett, 2013 , vol. 24, # 13 art. no. ST-2013-B0413-L, p. 1728 - 1734
反应条件
Birman's catalyst; trimethylacetic anhydride; N-ethyl-N,N-diisopropylamine in dichloromethane
T=20°C; 12 h; optical yield given as percent eeenantioselective reaction;
参考文献
Shiina, Isamu; Nakata, Kenya; Sugimoto, Masuhiro; Onda, Yu-Suke; Iizumi, Takashi; Ono, Keisuke
Heterocycles, 2009 , vol. 77, # 2 p. 801 - 810
反应条件
(1S,2R)-(+)-erythro-2-amino-1,2-diphenylethanol; benzoic acid in water; acetonitrile
T=20°C;
参考文献
Kodama, Koichi; Sekine, Eriko; Hirose, Takuji
Chemistry - A European Journal, 2011 , vol. 17, # 41 p. 11527 - 11534