2-甲基-1-苯基-1-丙醇合成路线 （共 136 条）
反应条件
1: 1-iodo-tridecafluoro-hexane; isopropylmagnesium chloride With bis(cyclopentadienyl)titanium dichloride in 1,4-dioxane; diethyl ether T=-78°C; 2 h; Inert atmosphere; 2: benzaldehyde in 1,4-dioxane; diethyl ether T=20°C; 2 h; Inert atmosphere;
参考文献
Chemistry - A European Journal, , vol. 20, # 8 p. 2382 - 2386
反应条件
1: 91 percent / pyridine / 0 °C 2: 98 percent / LiAlH4 / diethyl ether / Heating View Scheme
参考文献
Helvetica Chimica Acta, , vol. 65, # 5 p. 1602 - 1606
反应条件
1: 86 percent / LiAlH4 / diethyl ether / Heating 2: 91 percent / pyridine / 0 °C 3: 98 percent / LiAlH4 / diethyl ether / Heating View Scheme
参考文献
Helvetica Chimica Acta, , vol. 65, # 5 p. 1602 - 1606
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron, , vol. 42, # 15 p. 4235 - 4246
反应条件
titanium tetrachloride; zinc in tetrahydrofuran 20 h; Heating; Further byproducts given;
参考文献
Chemische Berichte, , vol. 115, # 12 p. 3697 - 3705
反应条件
1.1: magnesium sulfate / diethyl ether / 20 °C 2.1: bis(1,5-cyclooctadiene)nickel (0); Ipr.HCl; cesium fluoride / 1,4-dioxane; toluene / 0.5 h / 20 °C / Inert atmosphere 2.2: 10 h / 60 °C / Inert atmosphere View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 50, # 31 p. 7022 - 7026
反应条件
T=95 - 150°C; P=147102 - 220652 Torr; Hydrogenation;
参考文献
Journal of the American Chemical Society, , vol. 61, p. 3364,3369
反应条件
1.1: magnesium sulfate / diethyl ether / 20 °C 2.1: bis(1,5-cyclooctadiene)nickel (0); Ipr.HCl; cesium fluoride / 1,4-dioxane; toluene / 0.5 h / 20 °C / Inert atmosphere 2.2: 60 °C / Inert atmosphere View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 50, # 31 p. 7022 - 7026
反应条件
Coprinus peroxidase (CiP); 2-methoxy-phenol in water T=96°C; 20 h; phosphate buffer pH 7.0; enzyme-catalyzed kinetic resolution of chiral hydroperoxides in the presence and absence of guaiacol; selectivity; enantiomeric excess; CiP-catalyzed disproportionation; radical formation; mechanism; CiP-catalyzed sulfoxidation; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 64, # 13 p. 4834 - 4839
反应条件
T=25°C; P=1103.3 - 2206.5 Torr; Hydrogenation;
参考文献
Journal of the American Chemical Society, , vol. 65, p. 1984,1985
