N,N-二甲基苯甲酰胺合成路线 （共 319 条）
反应条件
1: 1.) PhMe2SiLi / 1.) THF, -78 to -20 deg C, 1.5 h 2: 73 percent / H2O, HCl View Scheme
参考文献
Fleming, Ian; Mack, Stephen R.; Clark, Barry P.
Chemical Communications, 1998 , # 6 p. 713 - 714
反应条件
1: 2.) n-BuLi / 1.) benzene, 0 deg C, 30 min. 2.) 5 h, room temp. 2: 2.) H2O,H(1+) / 1.) THF, benzene, -42 deg C, 30 min. View Scheme
参考文献
Comins, Daniel L.; Brown, Jack D.
Tetrahedron Letters, 1983 , vol. 24, # 49 p. 5465 - 5468
反应条件
1: N,N-dimethyl benzamide With bis(trichloromethyl) carbonate in tetrachloromethane T=0°C; 2: pyrrole in tetrachloromethane T=40 - 50°C; Vilsmeier-Haack reaction; 1 h; 3: With sodium hydroxide in tetrachloromethane
参考文献
Shi; Su; Shan
Journal of the Indian Chemical Society, 2005 , vol. 82, # 11 p. 1019 - 1021
反应条件
Yield given. Multistep reaction;
参考文献
Gharpure; Stoller; Bellamy; Firnau; Snieckus
Synthesis, 1991 , # 12 p. 1079 - 1082
反应条件
1: phosgene / CH2Cl2 2: triethylamine / CH2Cl2 3: hydrazinium chloride, triethylamine / CH2Cl2; tetrahydrofuran View Scheme
参考文献
Barrett, Anthony G. M.; Read, Roger W.; Barton, Derek H. R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2184 - 2190
反应条件
1: 75 percent / LiTMP / tetrahydrofuran / -78 °C 2: 1.) t-BuLi/TMEDA / 1.) THF, -78 deg C 3: 1.) TBAF 2.) Et3BHLi / 1.) THF, RT 2.) THF, from -20 to 0 deg C View Scheme
参考文献
Tetrahedron Letters, , vol. 30, # 43 p. 5841 - 5844
反应条件
1: 1.) POCl3 / 1.) 1,2-dichloroethane, reflux, 1 h, 2.) 1,2-dichloroethane, reflux, 24 h 2: 64 percent / K2CO3 / methanol; H2O / 0.5 h / Heating View Scheme
参考文献
Franco, Fidencio; Greenhouse, Robert; Muchowski, Joseph M.
Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1682 - 1688
反应条件
1: 1.) n-BuLi, N,N,N',N'-tetramethylethylenediamine / 1.) THF, a) -78 deg C, 0.5 h, b) -23 deg C, 0.5 h, 2.) a) -78 deg C, 2 h, b) 20 deg C, 3 h 2: 95 percent / 50 percent sulphuric acid / 0.75 h / Heating View Scheme
参考文献
Epsztajn, Jan; Jozwiak, Andrzej; Czech, Krzysztof; Szczesniak, Aleksandra K.
Monatshefte fuer Chemie, 1990 , vol. 121, # 11 p. 909 - 921
反应条件
1: With oxalyl dichloride in diethyl ether T=0 - 20°C; 4 h; 2: With LiAlHSeH in tetrahydrofuran T=20°C; 3 h;
参考文献
Takahashi, Hitoe; Nishina, Atsuyoshi; Kimura, Hirokazu; Motoki, Kenji; Koketsu, Mamoru; Ishihara, Hideharu
European Journal of Pharmaceutical Sciences, 2004 , vol. 23, # 3 p. 207 - 211
反应条件
3,4,5-tris(2,4-di-t-butyl-6-methoxyphenyl)-3,4,5-triselenoxo-1,2-diselene-3,4,5-triphospholane in benzene T=90°C; 220 h;
参考文献
An, De-Lie; Toyota, Kozo; Yasunami, Masafumi; Yoshifuji, Masaaki
Chemistry Letters, 1995 , # 3 p. 199 - 200
