N,N-二甲基苯甲酰胺合成路线 （共 319 条）
反应条件
1: Cl2 / CCl4 / Irradiation
2: AlCl3
View Scheme
参考文献
Boehme,H. et al.
Liebigs Annalen der Chemie, 1979 , p. 1447 - 1455
反应条件
1: 1.) samarium(III) trifluoromethanesulfonate, s-butyllithium, hexamethylphosphoric triamide / 1.) THF, cyclohexane, room temperature, 1 h, 2.) THF, cyclohexane, room temperature, 1 h
2: 71 percent / samarium(III) trifluoromethanesulfonate, s-butyllithium, hexamethylphosphoric triamide / tetrahydrofuran; cyclohexane / 1 h / Ambient temperature
View Scheme
参考文献
Fukuzawa, Shin-Ichi; Mutoh, Keisuke; Tsuchimoto, Teruhisa; Hiyama, Tamejiro
Journal of Organic Chemistry, 1996 , vol. 61, # 16 p. 5400 - 5405
反应条件
tert.-butylhydroperoxide; [Fe(5,10,15,20-tetrakis-phenyl-porphyrinato)](1+) in dichloromethane
T=30°C; k, k/KM; Rate constantMechanism;
参考文献
Iley, Jim
Tetrahedron Letters, 1990 , vol. 31, # 34 p. 4921 - 4922
反应条件
tert.-butylhydroperoxide; 5,10,15,20-tetrakisphenylporphyrinatoiron(III) chloride in dichloromethane
T=30°C; Kinetics;
参考文献
Constantino, Luis; Iley, Jim
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 13 p. 1894 - 1900
反应条件
1: 1.) n-BuLi / 1.) THF, -78 deg C, 1 h; 2.) -78 deg C, 1 h
2: 86 percent / tetrahydrofuran / 12 h / Ambient temperature
3: 68 percent / DIBAL / diethyl ether / 1.5 h / -30 °C
4: 87 percent / p-toluenesulfonic acid / benzene / 1 h / Heating
View Scheme
参考文献
Mandai, Tadakatsu; Takeshita, Masahiro; Mori, Kazuhito; Kawada, Mikio; Otera, Junzo
Chemistry Letters, 1983 , p. 1909 - 1910
反应条件
tri-ruthenium(0)dodecacarbonyl; hydrogen; molybdenum hexacarbonate in ethylene glycol dimethyl ether
T=160°C; P=75007.5 Torr; 16 h; Inert atmosphere;
参考文献
Beamson, Graham; Papworth, Adam J.; Philipps, Charles; Smith, Andrew M.; Whyman, Robin
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 5 p. 869 - 883
反应条件
1.1: tert.-butyl lithium / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere
1.2: -78 - 20 °C / Inert atmosphere
1.3: 1 h / 20 °C / Inert atmosphere
2.1: titanium tetrachloride; zinc / tetrahydrofuran / 18 h / Reflux; Inert atmosphere
View Scheme
参考文献
Katsumoto, Kenta; Kitamura, Chitoshi; Kawase, Takeshi
European Journal of Organic Chemistry, 2011 , # 25 p. 4885 - 4891
反应条件
trichlorophosphate
T=90°C; 2 h;
参考文献
Murakami; Tani; Suzuki; et al.
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 11 p. 4707 - 4716
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.67 h / -78 - -50 °C
1.2: -78 - 0 °C
2.1: sulfuric acid / tetrahydrofuran; water / 24 h
View Scheme
参考文献
Creary, Xavier; Hinckley, Jenifer; Kraft, Casey; Genereux, Madeleine
Journal of Organic Chemistry, 2011 , vol. 76, # 7 p. 2062 - 2071
反应条件
samarium in tetrahydrofuran
T=50°C; 1.5 h;
参考文献
Imamoto, Tsuneo; Hatajima, Toshihiko; Takiyama, Nobuyuki; Takeyama, Toshiaki; Kamiya, Yasuo; Yoshizawa, Takeshi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 12 p. 3127 - 3135
