N,N-二甲基苯甲酰胺合成路线 （共 319 条）
反应条件
trichlorophosphate
T=120 - 130°C; Erwaermen des Reaktionsprodukts mit Natriumacetat und Wasser;
参考文献
Raison
Journal of the Chemical Society, 1949 , p. 3319,3323
反应条件
sodium perchlorate in water; acetonitrile
controlled-potential electrolysis; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Hall, Larry R.; Iwamoto, Reynold T.; Hanzlik, Robert P.
Journal of Organic Chemistry, 1989 , vol. 54, # 10 p. 2446 - 2451
反应条件
phosphorus pentachloride
T=115 - 120°C; man zersetzt das Reaktionsprodukt mit Wasser;
参考文献
Merck
Patent: DE168728 ;
Full Text Show Details
v. Braun
Chemische Berichte, 1904 , vol. 37, p. 2816
反应条件
sodium perchlorate
1.) CH3CN, H2O, electrolysis, 2.) ether, 60 deg C, 24 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Hall, Larry R.; Iwamoto, Reynold T.; Hanzlik, Robert P.
Journal of Organic Chemistry, 1989 , vol. 54, # 10 p. 2446 - 2451
反应条件
tert.-butylhydroperoxide; 5,10,15,20-tetrakisphenylporphyrinatoiron(III) chloride in dichloromethane
T=30°C; Kinetics;
参考文献
Constantino, Luis; Iley, Jim
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 13 p. 1894 - 1900
反应条件
tert.-butyl lithium
1.) THF-pentane, -78 deg C, 2 h, 2.) -> RT, 1 h;
参考文献
Rawal, Viresh H.; Akiba, Mitsuo; Cava, Michael P.
Synthetic Communications, 1984 , vol. 14, # 12 p. 1129 - 1140
反应条件
1: 1.) n-BuLi / 1.) THF, -78 deg C, 1 h; 2.) -78 deg C, 1 h
2: 86 percent / tetrahydrofuran / 12 h / Ambient temperature
View Scheme
参考文献
Mandai, Tadakatsu; Takeshita, Masahiro; Mori, Kazuhito; Kawada, Mikio; Otera, Junzo
Chemistry Letters, 1983 , p. 1909 - 1910
反应条件
dibenzoyl peroxide in tetrachloromethane
Heating;
参考文献
Caristi, C.; Cimino, G.; Ferlazzo, A.; Gattuso, M.; Parisi, M.
Tetrahedron Letters, 1983 , vol. 24, # 26 p. 2685 - 2688
反应条件
1: 5-bromo-2-fluoro-4-methoxybenzaldehyde dimethylacetal in tetrahydrofuran
T=-70°C; 0.333333 h;
2: With n-butyllithium in tetrahydrofuran; hexane
T=-70°C; 0.166667 h;
3: N,N-dimethyl benzamide With water; toluene-4-sulfonic acid
more than 3 stages;
参考文献
KYOWA HAKKO KOGYO CO., LTD.
Patent: WO2006/118256 A1, 2006 ;
Location in patent: Page/Page column 90 ;
反应条件
1: 1-[(p-bromophenyl)phenylmethylidene]-1H-cyclopropa[b]naphthalene With n-butyllithium in tetrahydrofuran
T=-78°C; 1 h;
2: N,N-dimethyl benzamide in tetrahydrofuran
T=-78 - 20°C;
参考文献
Halton, Brian; Jones, Carissa S.
European Journal of Organic Chemistry, 2004 , # 1 p. 138 - 146
