4-(4-苯基-丁基)-吗啉合成路线 （共 7 条）
反应条件
2-[(N,N-diisopropylamino)methyl]phenylboronic acid in toluene
aza-Baeyer-Villiger Reaction; 20 h; Heating / reflux; Product distribution / selectivity;
参考文献
UNIVERSITY OF DURHAM
Patent: WO2004/113351 A2, 2004 ;
Location in patent: Page 43 ;
反应条件
NiCl2((PPh3)P)2 in tetrahydrofuran
T=20°C; 2 h;
参考文献
Lemoucheux; Rouden; Lasne
Tetrahedron Letters, 2000 , vol. 41, # 51 p. 9997 - 10001
反应条件
palladium on activated charcoal; ethanol
Hydrogenation;
参考文献
Cromwell et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 4412,4415
反应条件
1: diethyl ether
2: palladium/charcoal; ethanol / Hydrogenation
View Scheme
参考文献
Cromwell et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 4412,4415
反应条件
1: 160 - 167 °C
2: palladium/charcoal; ethanol / Hydrogenation
View Scheme
参考文献
Cromwell et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 4412,4415
参考文献
Cromwell et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 4412,4415
反应条件
1: 0.08 h / Heating
2: 51 percent / NiCl2(PPh3)2 / tetrahydrofuran / 2 h / 20 °C
View Scheme
参考文献
Lemoucheux; Rouden; Lasne
Tetrahedron Letters, 2000 , vol. 41, # 51 p. 9997 - 10001
