反应条件
1: sodium dithionite / water; ethanol / 1 h / 60 °C
2: trichlorophosphate / 2 h / 110 °C
3: N,N-dimethyl-formamide / 4 h / 45 °C
4: N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile / tetrachloromethane / 3 h / 80 °C
5: silver nitrate; water / ethanol / 1 h / 20 °C
View Scheme
参考文献
Surivet, Jean-Philippe; Zumbrunn, Cornelia; Rueedi, Georg; Hubschwerlen, Christian; Bur, Daniel; Bruyere, Thierry; Locher, Hans; Ritz, Daniel; Keck, Wolfgang; Seiler, Peter; Kohl, Christopher; Gauvin, Jean-Christophe; Mirre, Azely; Kaegi, Verena; Dos Santos, Marina; Gaertner, Mika; Delers, Jonathan; Enderlin-Paput, Michel; Boehme, Maria
Journal of Medicinal Chemistry, 2013 , vol. 56, # 18 p. 7396 - 7415