1: C15H23ClO2 With 1-N,N-dimethylaminonaphthalene; lithium in tetrahydrofuran
T=-65°C; 2 h;
2: methyl iodide in tetrahydrofuran
T=-65 - 20°C;
3: With hydrogenchloride in tetrahydrofuran
T=20°C; Further stages.;
1: 3-tert-butyl-4-hydroxy-5-methylphenylsulfide / 24 h / 220 °C
2: SiO2 / ethyl acetate; hexane
View Scheme
参考文献
Shook, Craig A.; Romberger, Matthew L.; Jung, Sang-Hun; Xiao, Manchao; Sherbine, James P.; Zhang, Birong; Lin, Fu-Tyan; Cohen, Theodore
Journal of the American Chemical Society, 1993 , vol. 115, # 23 p. 10754 - 10773
1: KH / tetrahydrofuran / 18 h
2: 3-tert-butyl-4-hydroxy-5-methylphenylsulfide / 24 h / 220 °C
3: SiO2 / ethyl acetate; hexane
View Scheme
参考文献
Shook, Craig A.; Romberger, Matthew L.; Jung, Sang-Hun; Xiao, Manchao; Sherbine, James P.; Zhang, Birong; Lin, Fu-Tyan; Cohen, Theodore
Journal of the American Chemical Society, 1993 , vol. 115, # 23 p. 10754 - 10773
