顺式-1,2-二羟甲基乙烯合成路线 （共 151 条）
反应条件
hydrogenchloride in water T=20°C; 3 h;
参考文献
Birck, Matthew R.; Clinch, Keith; Gainsford, Graeme J.; Schramm, Vern L.; Tyler, Peter C.
Helvetica Chimica Acta, 2009 , vol. 92, # 5 p. 823 - 838
反应条件
1: With sodium periodate; acetic acid; lithium bromide T=95°C; Prevost-Woodward reaction; 18 h; 2: With potassium carbonate in methanol T=25°C; 24 h;
参考文献
Emmanuvel, Lourdusamy; Ali Shaikh, Tanveer Mahammad; Sudalai, Arumugam
Organic Letters, 2005 , vol. 7, # 22 p. 5071 - 5074
反应条件
1,2,3-Benzotriazole; thionyl chloride in dichloromethane T=20°C; Substitution;
参考文献
Chaudhari, Sachin S.; Akamanchi, Krishnacharya G.
Synlett, 1999 , # 11 p. 1763 - 1765
参考文献
BASF
Patent: DE857369 , 1941 ;
Full Text Show Details
Reppe et al.
Justus Liebigs Annalen der Chemie, 1955 , vol. 596, p. 65
反应条件
1: cis-1,4-dihydroxy-2-butene With sodium hydride in tetrahydrofuran; dimethyl sulfoxide T=20°C; 0.5 h; 2: p-methoxybenzyl chloride With tetra-(n-butyl)ammonium iodide in tetrahydrofuran; dimethyl sulfoxide T=60°C;
参考文献
Schomaker, Jennifer M.; Pulgam, Veera Reddy; Borhan, Babak
Journal of the American Chemical Society, 2004 , vol. 126, # 42 p. 13600 - 13601
反应条件
Amberlyst-15 in dichloromethane 3 h; Reflux; regioselective reaction;
参考文献
Chavan, Subhash P.; Harale, Kishor R.
Tetrahedron Letters, 2012 , vol. 53, # 35 p. 4683 - 4686
反应条件
(-)-10-CSA in dichloromethane T=0 - 20°C; Inert atmosphere;
参考文献
Sreedhar, Eppakayala; Venkanna, Arramshetti; Chandramouli, Nagula; Babu, K. Suresh; Rao, Janaswamy Madhusudana
European Journal of Organic Chemistry, 2011 , # 6 p. 1078 - 1083
反应条件
potassium hydroxide in dimethyl sulfoxide T=0 - 20°C;
参考文献
De Carne-Carnavalet, Benoit; Archambeau, Alexis; Meyer, Christophe; Cossy, Janin; Folleas, Benoit; Brayer, Jean-Louis; Demoute, Jean-Pierre
Organic Letters, 2011 , vol. 13, # 5 p. 956 - 959
反应条件
1: With toluene-4-sulfonic acid in benzene Heating; 2: With diisobutylaluminium hydride in toluene T=0°C;
参考文献
Pisaneschi, Federica; Della Monica, Carmela; Cordero, Franca M; Brandi, Alberto
Tetrahedron Letters, 2002 , vol. 43, # 33 p. 5711 - 5714
反应条件
sulfuric acid in dichloromethane T=20°C; 4 h;
参考文献
Chavan, Subhash P.; Harale, Kishor R.
Tetrahedron Letters, 2012 , vol. 53, # 35 p. 4683 - 4686
